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US label: colorectal, non-squamous NSCLC, glioblastoma, renal, cervical and ovarian cancers; regimen-specific indicatio… · VEGF-A
US label: head and neck squamous cell cancer and biomarker-selected colorectal cancer; regimen-specific indications · EGFR
NSCLC (Stage III consolidation), SCLC, biliary tract, HCC · PD-L1
NSCLC, SCLC, HCC, TNBC, urothelial carcinoma, and others · PD-L1
Rheumatoid arthritis, psoriasis, Crohn's disease, ulcerative colitis, axial SpA · TNF-α
Multiple myeloma · CD38
HER2-positive breast cancer (including regimen-specific first-line and early-stage indications); HER2-low/ultralow brea… · HER2
Esophageal squamous cell carcinoma, gastric/GEJ adenocarcinoma, and first-line HER2-positive GEA with zanidatamab and c… · PD-1
Locally advanced or metastatic urothelial carcinoma · Nectin-4
Hyperlipidemia, ASCVD, HeFH · PCSK9
Plaque psoriasis, psoriatic arthritis, axial spondyloarthritis, hidradenitis suppurativa · IL-17A / IL-17F
Wet AMD, diabetic macular edema, macular edema following retinal vein occlusion · Ang-2 / VEGF-A
ALL, DLBCL, FL · CD19
Generalized myasthenia gravis (AChR antibody positive), chronic inflammatory demyelinating polyneuropathy · FcRn (neonatal Fc receptor)
Unresectable or metastatic melanoma after PD-1 blockade · Polyclonal tumor neoantigens (TIL)
Severe asthma add-on maintenance, chronic rhinosinusitis with nasal polyps · TSLP (thymic stromal lymphopoietin)
Extensive-stage small cell lung cancer after platinum-based chemotherapy · DLL3 × CD3
Early symptomatic Alzheimer's disease (MCI or mild dementia) with confirmed amyloid pathology · Amyloid-beta protofibrils
First-line HER2-positive gastric, GEJ, or esophageal adenocarcinoma; previously treated HER2-positive biliary tract can… · HER2 (biparatopic)
FRα-positive platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer · FRα (folate receptor alpha)
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