CGT

57개 · ADC 890 · Antibody 4097 · CGT 2985 · 다음 갱신 D-6 · 마지막 9월 2일

PopularRecently updatedCuratedMost trialsNeeds refreshORRLatestPhase 3FDA approved57 programs
CGTCurated CoreFDAVertexApproved

exagamglogene autotemcel (Casgevy, exa-cel, CTX001)

Sickle cell disease with recurrent VOCs; transfusion-dependent β-thalassemia · BCL11A enhancer (CRISPR/Cas9) → HbF

#BCL11AenhancerCRISPRCas9HbF#CGT#Approved#FDA-approved#BioJungboMoa-pick+5
Trials 9Status Approved
CGTCurated CoreFDAbluebird bioApproved

lovotibeglogene autotemcel (Lyfgenia, lovo-cel, bb1111)

Sickle cell disease with recurrent vaso-occlusive events · βA-T87Q-globin (lentiviral)

#A-T87Q-globinlentiviral#CGT#Approved#FDA-approved#BioJungboMoa-pick+5
Trials 2Status Approved
CGTLimited DatastaleThomas Martin, MDPhase 1

Chimeric Antigen Receptor T cells (CAR-T, Chimeric Antigen Receptor T cells, Chimeric Antigen Receptor T cells (CAR-T) Targeting BCMA)

Multiple Myeloma; Recurrent Multiple Myeloma · BCMA

#BCMA#CGT#Phase1#Popular#cell-gene-therapy+5
Trials 211Status Discontinued
CGTStandard DatabasestaleMerck Sharp & Dohme LLCPhase 3

Recombinant Interferon Alfa-2b (Recombinant Interferon Alfa-2b)

Recurrent Melanoma; Stage IIIA Cutaneous Melanoma AJCC v7 · HER2

#HER2#CGT#Phase3#Popular#cell-gene-therapy+5
Trials 83Status Recruiting
CGTLimited DatastaleIstituto Clinico HumanitasPreclinical

immune evaluation (immune evaluation)

Oligorecurrent and Oligoprogressive Prostate Cancer Patients · Oligorecurrent and Oligoprogressive Pros

#OligorecurrentandOligoprogressiv#CGT#Preclinical#Popular#cell-gene-therapy+4
Trials 61Status Recruiting
CGTLimited DatastaleTransMolecularPhase 1

Chlorotoxin (EQ, Chlorotoxin, Chlorotoxin (EQ)-CD28-CD3zeta-CD19t-expressing CAR T-lymphocytes (via ICT delivery))

Recurrent Glioblastoma; Recurrent Malignant Glioma · CD19

#CD19#CGT#Phase1#Popular#cell-gene-therapy+5
Trials 60Status Recruiting
CGTLimited DatastaleTransMolecularPhase 1

Chlorotoxin (EQ, Chlorotoxin, Chlorotoxin (EQ)-CD28-CD3zeta-CD19t-expressing CAR T-lymphocytes (via ICT/ICV dual delivery))

Recurrent Glioblastoma; Recurrent Malignant Glioma · CD19

#CD19#CGT#Phase1#Popular#cell-gene-therapy+5
Trials 60Status Recruiting
CGTLimited DatastaleLion TCR Pte. Ltd.Phase 1

Biological: TCR-T (Biological: TCR-T)

Recurrent Hepatocellular Carcinoma · Recurrent Hepatocellular Carcinoma

#RecurrentHepatocellularCarcinoma#CGT#Phase1#Popular#cell-gene-therapy+4
Trials 58Status Active
CGTLimited DatastaleRoyan InstitutePhase 1

NK cell therapy (NK cell therapy)

Glioblastoma Multiform; Recurrent Glioblastoma · Glioma Glioblastoma Multiforme

#GliomaGlioblastomaMultiforme#CGT#Phase1#Popular#cell-gene-therapy+5
Trials 58Status Active
CGTStandard DatabasestaleGeneplus-Beijing Co. Ltd.Phase 2

natural killer cell infusion (natural killer cell infusion)

Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood B-Lymphoblastic Lymphoma · Recurrent B-Cell Childhood Acute Lymphob

#RecurrentB-CellChildhoodAcuteLym#CGT#Phase2#Popular#cell-gene-therapy+5
Trials 58Status Active
CGTLimited DatastaleMarzieh EbrahimiPhase 1

Allogenic NK cells infusion (Allogenic NK cells infusion)

Neuroblastoma, Recurrent, Refractory; Neuroblastoma (NB) · FRα

#FR#CGT#Phase1#Popular#cell-gene-therapy+5
Trials 56Status Recruiting
CGTLimited DatastaleInternational Brain Research Fo…Phase 2

Quercetin (Quercetin)

Recurrent Multiple Myeloma; Refractory Multiple Myeloma · FRα

#FR#CGT#Phase2#Popular#cell-gene-therapy+5
Trials 54Status Recruiting
CGTLimited DatastaleSecuraBioPhase 1

Duvelisib (Duvelisib)

Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma · FRα

#FR#CGT#Phase1#cell-gene-therapy#CAR-T+5
Trials 45Status Active
CGTLimited DatastaleRui Therapeutics Co., LtdPhase 1

anti-CD19 CAR-NK cells (anti-CD19 CAR-NK cells)

Refractory/Recurrent Central Nervous System Lymphoma · CD19

#CD19#CGT#Phase1#cell-gene-therapy#CAR-T+5
Trials 32Status Active
CGTStandard DatabasestaleQingdao Haier Biotechnology Co.…Phase 2

autologous NK cell (autologous NK cell)

NK Cell; B-cell Lymphoma Recurrent · FRα

#FR#CGT#Phase2#cell-gene-therapy#CAR-T+4
Trials 31Status Recruiting
CGTLimited DatastaleDutch Cancer SocietyPhase 1

UCB-NK cells (UCB-NK cells)

Recurrent Ovarian Carcinoma; Recurrent Fallopian Tube Carcinoma · Recurrent Ovarian Carcinoma

#RecurrentOvarianCarcinoma#CGT#Phase1#cell-gene-therapy#CAR-T+3
Trials 16Status Active
CGTLimited DatastaleGuangdong Xiangxue Precision Me…Phase 1

Anti-NY-ESO-1 TCR transduced T cells (Anti-NY-ESO-1 TCR transduced T cells)

Lung Cancer, Nonsmall Cell, Recurrent · Lung Cancer, Nonsmall Cell, Recurrent

#LungCancerNonsmallCellRecurrent#CGT#Phase1#cell-gene-therapy#CAR-T+5
Trials 9Status Active
CGTLimited DatastaleSichuan UniversityPhase 1

EpCAM CAR-T cells (EpCAM CAR-T cells)

Malignant Neoplasm of Nasopharynx TNM Staging Distant Metastasis (M); Breast Cancer Recurrent · Malignant Neoplasm of Nasopharynx TNM St

#MalignantNeoplasmofNasopharynxTN#CGT#Phase1#cell-gene-therapy#CAR-T+3
Trials 7Status Active
CGTLimited DatastaleCity of Hope Medical CenterPhase 2

CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes)

Recurrent Mantle Cell Lymphoma; Refractory Mantle Cell Lymphoma · EGFR

#EGFR#CGT#Phase2#cell-gene-therapy#CAR-T+4
Trials 6Status Recruiting
CGTLimited DatastaleCity of Hope Medical CenterPhase 1

CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes)

B Acute Lymphoblastic Leukemia; Recurrent Acute Lymphoblastic Leukemia · EGFR

#EGFR#CGT#Phase1#cell-gene-therapy#CAR-T+4
Trials 4Status Recruiting

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