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Catalyst · Landscape

향후 6개월 내 primary completion 예정인 활성 임상과 큐레이션·승인 프로그램의 phase 분포입니다. CT.gov completion date 기반 추정이며 공식 readout 일정과 다를 수 있습니다. RSS

파이프라인 Phase 분포

큐레이션·FDA·임상 3건 이상 프로그램 2029개 — catalyst 일정과 별도의 전체 파이프라인 스냅샷입니다.

Preclinical
132
Phase 1
491
Phase 2
979
Phase 3
293
Approved
134

Catalyst target · modality

향후 6개월 catalyst 26건 · 타깃·모달리티 분포

ADC 2Antibody 24
HER2
8
PD-1
7
PD-L1
3
Non-Small
2
Nectin-4
2
CLDN18.2
2
Solid
1
B-cell
1

향후 6개월 Catalyst(26 / 80)

활성 recruiting/enrolling 임상 · CT.gov completion 기준 · 상위 80건 표시

완료 예정프로그램PhaseStatusEndpoint신뢰도NCT
2026년 9월RamucirumabAntibody · Non-Small Cell Lung CancerPhase 3RecruitingProgression Free Survival (PFS) in all randomized participants; Overall Survival (OS) for 3L+ participants신뢰 높음NCT06346392
2026년 9월IpilimumabAntibody · HER2Phase 1Active, not recruitingIncidence of adverse events of entinostat and nivolumab in combination with ipilimumab신뢰 높음NCT02453620
2026년 9월Tecentriq (atezolizumab)Antibody · PD-L1Phase 1Active, not recruitingFeasibility of Neoadjuvant Cisplatin-Pemetrexed-Atezolizumab, Surgery +/- Radiation, and Maintenance Therapy.; Safety of Neoadjuvant Cisplatin-Pemetrexed-Atezolizumab, Surgery +/- Radiation, and Maintenance Therapy.보통NCT03228537
2026년 9월Herceptin (trastuzumab)Antibody · HER2Phase 2Active, not recruitingResponse to Neoadjuvant Chemotherapy Determined at Surgery (Lumpectomy or Mastectomy).보통NCT02827877
2026년 9월IpilimumabAntibody · HER2Phase 1Active, not recruitingIncidence of adverse events; Dose-limiting toxicity (DLT); Feasibility (neoadjuvant therapy); Feasibility (adjuvant therapy); Overall Survival보통NCT04003649
2026년 9월Keytruda (pembrolizumab)Antibody · PD-1Phase 3Active, not recruitingProgression-free Survival (PFS)신뢰 높음NCT03914612
2026년 9월Keytruda (pembrolizumab)Antibody · PD-1N/AActive, not recruitingCentral and local clinical genotyping to facilitate accrual to the adjuvant Intergroup studies, E4512 and A081105; Feasibility of research grade formalin-fixed, paraffin-embedded tissue collection for Center for Cancer Genomics (CCG) analysis신뢰 높음NCT02194738
2026년 9월Keytruda (pembrolizumab)Antibody · PD-1Phase 2Active, not recruitingObjective Response Rate as Assessed by Independent Review Committee (IRC) per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1; Percentage of Participants Experiencing Dose-limiting Toxicities (DLTs) per Dose Level in the Safety Run-in Cohorts신뢰 높음NCT05186974
2026년 9월IpilimumabAntibody · HER2Phase 2Active, not recruitingProportion of patients who have objective tumor response (complete or partial) by modified RECIST 1.1 in patients with clear cell carcinomas treated with nivolumab or the combination of nivolumab and ipilimumab보통NCT03355976
2026년 9월Padcev (enfortumab vedotin)ADC · Nectin-4N/ARecruitingChange from Baseline in Circulating EV Concentration신뢰 높음NCT07558447
2026년 9월Keytruda (pembrolizumab)Antibody · PD-1Phase 2Active, not recruitingPathological Complete Response보통NCT04869137
2026년 9월Tecentriq (atezolizumab)Antibody · PD-L1Phase 2Active, not recruitingNumber of patients who experience complete or partial tumor response신뢰 높음NCT03526432
2026년 9월Tecentriq (atezolizumab)Antibody · PD-L1Phase 2Active, not recruitingFailure-free Rate at 2 Years보통NCT04262154
2026년 9월Keytruda (pembrolizumab)Antibody · PD-1Phase 2RecruitingProportion of Participants with Progression-Free Survival신뢰 높음NCT04253964
2026년 9월RamucirumabAntibody · Non-Small Cell Lung CancerPhase 2RecruitingTo estimate overall response rate신뢰 높음NCT04332367
2026년 9월Vyloy (zolbetuximab)Antibody · CLDN18.2 (claudin-18.2)Phase 3Active, not recruitingProgression Free Survival (PFS)신뢰 높음NCT03504397
2026년 9월Padcev (enfortumab vedotin)ADC · Nectin-4Phase 2Active, not recruitingCohorts 1-8: Confirmed Overall Response Rate (ORR) (Complete Response [CR] and Partial Response [PR]) Per Response Evaluation Criteria in Solid Tumors (RECIST) Version (V)1.1 Per Investigator Assessment; Cohort 9: Confirmed ORR (CR and PR) Per RECIST V1.1 Per Investigator Assessment신뢰 높음NCT04225117
2026년 9월Herceptin (trastuzumab)Antibody · HER2Phase 2Active, not recruitingNumber of Participants With Complete Pathologic Response (pCR)신뢰 높음NCT03879577
2026년 9월Vyloy (zolbetuximab)Antibody · CLDN18.2 (claudin-18.2)Phase 3Active, not recruitingProgression Free Survival (PFS)신뢰 높음NCT03653507
2026년 9월CemiplimabAntibody · Solid TumorRecruitingIncidence of treatment-related sexual dysfuction in male patients with ANSCLC신뢰 높음NCT06532149
2026년 9월IpilimumabAntibody · HER2Phase 1Active, not recruitingRecommended phase II dose (Phase I); Incidence of adverse events (Phase I)신뢰 높음NCT02496208
2026년 9월Herceptin (trastuzumab)Antibody · HER2Phase 2Active, not recruitingPathological Complete Response rate (pCR)신뢰 높음NCT04172259
2026년 9월IvonescimabAntibody · HER2Phase 2Not yet recruiting6-month-PFS rate보통NCT06991491
2026년 9월Keytruda (pembrolizumab)Antibody · PD-1Phase 1RecruitingDose Limiting Toxicity (DLT); Non-Tolerated Dose (NTD); Maximum Tolerated Dose (MTD); Progression Free Survival (PFS) (Randomized Cohort only); Adverse Events (AEs)신뢰 높음NCT05403554
2026년 9월ObinutuzumabAntibody · B-cell LymphomaN/ARecruitingProgression-free survival rate at 24 months신뢰 높음NCT05950997
2026년 9월Keytruda (pembrolizumab)Antibody · PD-1Phase 1, Phase 2Not yet recruitingsafety rate; objective response rate보통NCT05286320
  • 2026년 9월신뢰 높음
    Ramucirumab

    Antibody · Non-Small Cell Lung Cancer · Phase 3

    Progression Free Survival (PFS) in all randomized participants; Overall Survival (OS) for 3L+ participants

    NCT06346392
  • 2026년 9월신뢰 높음
    Ipilimumab

    Antibody · HER2 · Phase 1

    Incidence of adverse events of entinostat and nivolumab in combination with ipilimumab

    NCT02453620
  • 2026년 9월보통
    Tecentriq (atezolizumab)

    Antibody · PD-L1 · Phase 1

    Feasibility of Neoadjuvant Cisplatin-Pemetrexed-Atezolizumab, Surgery +/- Radiation, and Maintenance Therapy.; Safety of Neoadjuvant Cisplatin-Pemetrexed-Atezolizumab, Surgery +/- Radiation, and Maintenance Therapy.

    NCT03228537
  • 2026년 9월보통
    Herceptin (trastuzumab)

    Antibody · HER2 · Phase 2

    Response to Neoadjuvant Chemotherapy Determined at Surgery (Lumpectomy or Mastectomy).

    NCT02827877
  • 2026년 9월보통
    Ipilimumab

    Antibody · HER2 · Phase 1

    Incidence of adverse events; Dose-limiting toxicity (DLT); Feasibility (neoadjuvant therapy); Feasibility (adjuvant therapy); Overall Survival

    NCT04003649
  • 2026년 9월신뢰 높음
    Keytruda (pembrolizumab)

    Antibody · PD-1 · Phase 3

    Progression-free Survival (PFS)

    NCT03914612
  • 2026년 9월신뢰 높음
    Keytruda (pembrolizumab)

    Antibody · PD-1 · N/A

    Central and local clinical genotyping to facilitate accrual to the adjuvant Intergroup studies, E4512 and A081105; Feasibility of research grade formalin-fixed, paraffin-embedded tissue collection for Center for Cancer Genomics (CCG) analysis

    NCT02194738
  • 2026년 9월신뢰 높음
    Keytruda (pembrolizumab)

    Antibody · PD-1 · Phase 2

    Objective Response Rate as Assessed by Independent Review Committee (IRC) per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1; Percentage of Participants Experiencing Dose-limiting Toxicities (DLTs) per Dose Level in the Safety Run-in Cohorts

    NCT05186974
  • 2026년 9월보통
    Ipilimumab

    Antibody · HER2 · Phase 2

    Proportion of patients who have objective tumor response (complete or partial) by modified RECIST 1.1 in patients with clear cell carcinomas treated with nivolumab or the combination of nivolumab and ipilimumab

    NCT03355976
  • 2026년 9월신뢰 높음
    Padcev (enfortumab vedotin)

    ADC · Nectin-4 · N/A

    Change from Baseline in Circulating EV Concentration

    NCT07558447
  • 2026년 9월보통
    Keytruda (pembrolizumab)

    Antibody · PD-1 · Phase 2

    Pathological Complete Response

    NCT04869137
  • 2026년 9월신뢰 높음
    Tecentriq (atezolizumab)

    Antibody · PD-L1 · Phase 2

    Number of patients who experience complete or partial tumor response

    NCT03526432
  • 2026년 9월보통
    Tecentriq (atezolizumab)

    Antibody · PD-L1 · Phase 2

    Failure-free Rate at 2 Years

    NCT04262154
  • 2026년 9월신뢰 높음
    Keytruda (pembrolizumab)

    Antibody · PD-1 · Phase 2

    Proportion of Participants with Progression-Free Survival

    NCT04253964
  • 2026년 9월신뢰 높음
    Ramucirumab

    Antibody · Non-Small Cell Lung Cancer · Phase 2

    To estimate overall response rate

    NCT04332367
  • 2026년 9월신뢰 높음
    Vyloy (zolbetuximab)

    Antibody · CLDN18.2 (claudin-18.2) · Phase 3

    Progression Free Survival (PFS)

    NCT03504397
  • 2026년 9월신뢰 높음
    Padcev (enfortumab vedotin)

    ADC · Nectin-4 · Phase 2

    Cohorts 1-8: Confirmed Overall Response Rate (ORR) (Complete Response [CR] and Partial Response [PR]) Per Response Evaluation Criteria in Solid Tumors (RECIST) Version (V)1.1 Per Investigator Assessment; Cohort 9: Confirmed ORR (CR and PR) Per RECIST V1.1 Per Investigator Assessment

    NCT04225117
  • 2026년 9월신뢰 높음
    Herceptin (trastuzumab)

    Antibody · HER2 · Phase 2

    Number of Participants With Complete Pathologic Response (pCR)

    NCT03879577
  • 2026년 9월신뢰 높음
    Vyloy (zolbetuximab)

    Antibody · CLDN18.2 (claudin-18.2) · Phase 3

    Progression Free Survival (PFS)

    NCT03653507
  • 2026년 9월신뢰 높음
    Cemiplimab

    Antibody · Solid Tumor ·

    Incidence of treatment-related sexual dysfuction in male patients with ANSCLC

    NCT06532149
  • 2026년 9월신뢰 높음
    Ipilimumab

    Antibody · HER2 · Phase 1

    Recommended phase II dose (Phase I); Incidence of adverse events (Phase I)

    NCT02496208
  • 2026년 9월신뢰 높음
    Herceptin (trastuzumab)

    Antibody · HER2 · Phase 2

    Pathological Complete Response rate (pCR)

    NCT04172259
  • 2026년 9월보통
    Ivonescimab

    Antibody · HER2 · Phase 2

    6-month-PFS rate

    NCT06991491
  • 2026년 9월신뢰 높음
    Keytruda (pembrolizumab)

    Antibody · PD-1 · Phase 1

    Dose Limiting Toxicity (DLT); Non-Tolerated Dose (NTD); Maximum Tolerated Dose (MTD); Progression Free Survival (PFS) (Randomized Cohort only); Adverse Events (AEs)

    NCT05403554
  • 2026년 9월신뢰 높음
    Obinutuzumab

    Antibody · B-cell Lymphoma · N/A

    Progression-free survival rate at 24 months

    NCT05950997
  • 2026년 9월보통
    Keytruda (pembrolizumab)

    Antibody · PD-1 · Phase 1, Phase 2

    safety rate; objective response rate

    NCT05286320