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ADC 890 · Antibody 4097 · CGT 2985 · 다음 갱신 D-6 · 마지막 9월 2일

PopularRecently updatedCuratedMost trialsNeeds refreshORRLatestPhase 3FDA approved9 programs
AntibodyCurated CoreFDARocheApproved

faricimab (Vabysmo, RG7716, faricimab-svoa)

Wet AMD, diabetic macular edema, macular edema following retinal vein occlusion · Ang-2 / VEGF-A

#Ang-2VEGF-A#Antibody#Approved#FDA-approved#BioJungboMoa-pick+5
Trials 53Status Approved
CGTAAVCurated CoreFDASpark TherapeuticsApproved

voretigene neparvovec (Luxturna, AAV2-hRPE65v2, voretigene neparvovec-rzyl)

Inherited retinal dystrophy due to confirmed biallelic RPE65 mutations · RPE65 (AAV2)

#RPE65AAV2#CGT#Approved#FDA-approved#BioJungboMoa-pick+5
Trials 7Status Approved
CGTLimited DatastaleNanoscope Therapeutics Inc.Phase 2

Gene Therapy product:vMCO-I (Gene Therapy product:vMCO-I)

Retinitis Pigmentosa; Retinal Diseases · Retinitis Pigmentosa

#RetinitisPigmentosa#CGT#Phase2#cell-gene-therapy#CAR-T+3
Trials 2Status Active
CGTAAVLimited DatastaleGenentech, Inc.Preclinical

AAV2-hRPE65v2 (AAV2-hRPE65v2)

Inherited Retinal Dystrophy Due to RPE65 Mutations · Multi-target

#Multi-target#CGT#Preclinical#cell-gene-therapy#CAR-T+3
Trials 1Status Recruiting
AntibodyLimited DatastaleRochePhase 3

Active bevacizumab and Active dexamethasone (Active bevacizumab and Active dexamethasone)

Non-Ischemic Central Retinal Vein Occlusion · Non-Ischemic Central Retinal Vein Occlus

#Non-IschemicCentralRetinalVeinOc#Antibody#Phase3#monoclonal-antibody#Roche
Trials 1Status Active
AntibodyLimited DatastaleRochePhase 3

injection Combined Bevacizumab and Fasudil (injection Combined Bevacizumab and Fasudil)

Retinal Vein Occlusion · Retinal Vein Occlusion

#RetinalVeinOcclusion#Antibody#Phase3#monoclonal-antibody#Roche
Trials 1Status Active
AntibodyLimited DatastaleRochePhase 3

injection bevacizumab (injection bevacizumab)

Retinal Vein Occlusion · Retinal Vein Occlusion

#RetinalVeinOcclusion#Antibody#Phase3#monoclonal-antibody#Roche
Trials 1Status Active
CGTLimited DatastaleUniversity of PennsylvaniaPhase 1

rAAV2-CBSB-hRPE65 (rAAV2-CBSB-hRPE65)

Amaurosis of Leber; Retinal Diseases · Amaurosis of Leber

#AmaurosisofLeber#CGT#Phase1#cell-gene-therapy#CAR-T+3
Trials 1Status Recruiting
CGTLimited DatastaleUniversity College, LondonPhase 2

rAAV 2/2.hRPE65p.hRPE65 (tgAAG76, tgAAG76 (rAAV 2/2.hRPE65p.hRPE65))

Retinal Degeneration · Retinal Degeneration

#RetinalDegeneration#CGT#Phase2#cell-gene-therapy#CAR-T+2
Trials 1Status Active