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HER2

223개 · ADC 1032 · Antibody 4683 · CGT 2713 · 다음 갱신 D-8 · 마지막 7월 21일

인기최근 업데이트큐레이션임상 많은갱신 필요ORR최신Phase 3FDA승인프로그램 223개
ADCBiologicstaleSuzhou Suncadia Biopharmaceutic…rezetecanPhase 3

SHR-A1811 (SHR-A1811)

Breast Cancer; HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
임상시험 62상태 RECRUITING
ADCBiologicstaleQuantumLeap Healthcare Collabor…Phase 2

Standard Therapy (Standard Therapy)

Breast Neoplasms; Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 9%임상시험 62상태 RECRUITING
ADCBiologicstaleRelmada Therapeutics, Inc.deruxtecan improved objecti…Phase 2

Control treatment arm (Control treatment arm)

Hormone Receptor(HR)-Positive, Low HER2 Advanced Breast Cancer Patients (HER2 IHC 1+ or 2+ & ISH Negative) · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
임상시험 61상태 RECRUITING
ADCBiologicstaleBioMérieuxderuxtecan plus fluoropyrim…Phase 2

Experimental treatment arm (Experimental treatment arm)

Hormone Receptor(HR)-Positive, Low HER2 Advanced Breast Cancer Patients (HER2 IHC 1+ or 2+ & ISH Negative) · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
임상시험 61상태 RECRUITING
ADCBiologicBristol-Myers SquibbreleasePhase 2

Taxane Chemotherapy (Taxane Chemotherapy)

HER2 + Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 81.1%임상시험 61상태 RECRUITING
ADCBiologicChipscreen Biosciences, Ltd.sPhase 3

taxane drug (taxane drug)

HER2-positive Metastatic Breast Cancer; First-line Treatment · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 81.1%임상시험 61상태 RECRUITING
ADCBiologicstaleSWOG Cancer Research NetworkDM1) and/or trastuzumab der…Phase 3

HER2-targeted Therapy (HER2-targeted Therapy)

Anatomic Stage IV Breast Cancer AJCC v8; Metastatic HER2-Positive Breast Carcinoma · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 18.75%임상시험 59상태 RECRUITING
ADCBiologicstaleRocheDM1 via butelase-1 with ABD…Phase 3

T-DM1 (Trastuzumab emtansine, Trastuzumab emtansine (T-DM1))

Advanced Breast Cancer; Objective Response Rate · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 69.7%임상시험 59상태 RECRUITING
ADCBiologicstaleJules Bordet InstituteReleasePhase 2

Neratinib (Neratinib)

Breast Cancer; Brain Metastases · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 57.1%임상시험 58상태 RECRUITING
AntibodyRocheDM1Phase 2

trastuzumab (Herceptin, Pertuzumab and Trastuzumab)

Breast Neoplasms; Breast Cancer · HER2

#HER2#Antibody#Phase2#인기#항체+5
효능 ORR 88.6%임상시험 58상태 RECRUITING
ADCBiologicSWOG Cancer Research NetworkDeruxtecan-Dlnk Quantificat…Phase 3

Taxane Compound (Taxane Compound)

Anatomic Stage IV Breast Cancer AJCC v8; Metastatic HER2-Positive Breast Carcinoma · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 69.3%임상시험 58상태 RECRUITING
ADCBiologicstaleAssistance Publique - Hôpitaux …Phase 2

Adjuvant Systemic Therapy (Adjuvant Systemic Therapy)

Breast Cancer; HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 10%임상시험 57상태 RECRUITING
AntibodyRochederuxtecan alone or followe…Phase 3

trastuzumab (Herceptin, Paclitaxel + Trastuzumab)

HER2-positive Breast Cancer · HER2

#HER2#Antibody#Phase3#인기#항체+5
효능 ORR 80%임상시험 57상태 RECRUITING
ADCBiologicstaleRocheDM1 via butelase-1 with ABD…Phase 2

ado-trastuzumab emtansine (Kadcyla, T-DM1)

Bone Metastases; HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 69.7%임상시험 57상태 ACTIVE
ADCBiologicstaleRemeGen Co., Ltd.sPhase 2

disitamab vedotin (Disitamab Vedotin, RC48)

Non-Muscle Invasive Bladder Cancer; HER2 · Gastric Cancer/Gastroesophageal Junction

#GastricCancerGastroesophagealJun#ADC#Phase2#인기#항체약물접합체+5
임상시험 56상태 RECRUITING
ADCBiologicstaleSeagen Inc.deruxtecan and tucatinibPhase 1

ONT-380 (Tucatinib, Tucatinib (ONT-380))

HER2 Positive Breast Cancers · HER2

#HER2#ADC#Phase1#인기#항체약물접합체+5
효능 ORR 100%임상시험 54상태 ACTIVE
ADCBiologicstaleQuantumLeap Healthcare Collabor…Phase 2

ABT-888 (ABT-888)

Breast Neoplasms; Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+4
효능 ORR 74.1%임상시험 53상태 RECRUITING
ADCBiologicstaleJiangsu HengRui Medicine Co., L…Phase 2

Famitinib (Famitinib)

Advanced Breast Cancer; Metastatic Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
임상시험 53상태 RECRUITING
ADCBiologicstaleFudan UniversityderuxtecanPhase 2

Dalpiciclib (Dalpiciclib)

HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+4
임상시험 52상태 RECRUITING
ADCBiologicstaleSWOG Cancer Research Networkderuxtecan (T-DXd) and tyro…Phase 3

Cyclin-Dependent Kinase 4 Inhibitor (Cyclin-Dependent Kinase 4 Inhibitor)

Anatomic Stage IV Breast Cancer AJCC v8; Metastatic HER2-Positive Breast Carcinoma · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 57.98%임상시험 50상태 RECRUITING

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