구조모아 (StructureMoa)항암 chemical structure spider web
방문EMD Serono
Temozolomide (TMZ)(EMD Serono)은 Advanced Solid Malignancies 표적 치료제로, Advanced Solid Malignancies 영역에서 개발·상용화 중입니다. 작용기전: targets were involved in multiple biological processes, cellular components, molecular functions, and signaling pathway. Phase 2에서 효능·안전성 신호를 검증 중입니다. PFS: 10.5. PK: t½ 5 h. 차별점: unique drug-disease intersection targets were obtained after merging the TMZ-disease and CoQ10-disease targets and five core t.
공개된 구조화 근거가 제한적입니다.
구조화 데이터
Advanced Solid Malignancies
Advanced Solid Malignancies
Recruiting
2026-09-02
Data Confidence · Low
Development Signal · Emerging
ADC) have shown potential in glioblastoma therapy, their clinic
SN-38 for the treatment of glioblastoma: Engi
linker to conjugate a vascular endothelial growth factor-targeting antibody with the c
unique drug-disease intersection targets were obtained after merging the TMZ-disease and CoQ10-disease targets and five core t
targets were involved in multiple biological processes, cellular components, molecular functions, and signaling pathway
immune-mediated clearance
apoptosis-related genes ( p53, p21, Bax, Bcl-2, Bcl-xL , and caspase-3 ) was analysed by reverse transcription-quantitative polym
biomarkers for nitrosative stress, and apoptosis using western blot analysis, flow cytometry and AnnexinV/PI
resistance mechanisms, constrains TMZ efficacy
구조화 데이터
xenografts to temozolomide treatment in a subcutaneous mouse
mouse
5
구조화 데이터
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다. 효능 수치는 선택한 등록 결과이며 전적응증 값이 아닙니다.
바이오정보모아는 연구·교육용 과학·의약품 개발 정보입니다. 진료, 진단, 치료 지침, 규제 자문이 아닙니다.
EMD Serono
Temozolomide (TMZ)(EMD Serono)은 Advanced Solid Malignancies 표적 치료제로, Advanced Solid Malignancies 영역에서 개발·상용화 중입니다. 작용기전: targets were involved in multiple biological processes, cellular components, molecular functions, and signaling pathway. Phase 2에서 효능·안전성 신호를 검증 중입니다. PFS: 10.5. PK: t½ 5 h. 차별점: unique drug-disease intersection targets were obtained after merging the TMZ-disease and CoQ10-disease targets and five core t.
공개된 구조화 근거가 제한적입니다.
구조화 데이터
Advanced Solid Malignancies
Advanced Solid Malignancies
Recruiting
2026-09-02
Data Confidence · Low
Development Signal · Emerging
ADC) have shown potential in glioblastoma therapy, their clinic
SN-38 for the treatment of glioblastoma: Engi
linker to conjugate a vascular endothelial growth factor-targeting antibody with the c
unique drug-disease intersection targets were obtained after merging the TMZ-disease and CoQ10-disease targets and five core t
targets were involved in multiple biological processes, cellular components, molecular functions, and signaling pathway
immune-mediated clearance
apoptosis-related genes ( p53, p21, Bax, Bcl-2, Bcl-xL , and caspase-3 ) was analysed by reverse transcription-quantitative polym
biomarkers for nitrosative stress, and apoptosis using western blot analysis, flow cytometry and AnnexinV/PI
resistance mechanisms, constrains TMZ efficacy
구조화 데이터
xenografts to temozolomide treatment in a subcutaneous mouse
mouse
5
구조화 데이터
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다. 효능 수치는 선택한 등록 결과이며 전적응증 값이 아닙니다.
바이오정보모아는 연구·교육용 과학·의약품 개발 정보입니다. 진료, 진단, 치료 지침, 규제 자문이 아닙니다.