CGT

2nd generation T cells (Patient Derived CD171 specific CAR T cells expressing EGFRt, Patient Derived CD171 specific CAR T cells expressing EGFRt (2nd generation T cells))

Neuroblastoma; Ganglioneuroblastoma · EGFR

CGTLimited DatastaleSeattle Children's HospitalPhase 1

3rd generation T cells (Patient Derived CD171 specific CAR T cells expressing EGFRt, Patient Derived CD171 specific CAR T cells expressing EGFRt (3rd generation T cells))

Neuroblastoma; Ganglioneuroblastoma · EGFR

long spacer 2nd generation T cells (Patient Derived CD171 specific CAR T cells expressing EGFRt, Patient Derived CD171 specific CAR T cells expressing EGFRt (long spacer 2nd generation T cells))

Neuroblastoma; Ganglioneuroblastoma · EGFR

CGTLimited DatastalePell Bio-Med Technology Co., Lt…Preclinical

Pell's lentiviral-based gene-edited immune cell therapy (Pell's lentiviral-based gene-edited immune cell therapy)

Diffuse Large B Cell Lymphoma; Large B-cell Lymphoma · Diffuse Large B Cell Lymphoma

#DiffuseLargeBCellLymphoma#CGT#Preclinical#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleOttawa Heart Institute Research…Phase 3

Point-of-care genetic screening with subsequent prasugrel administration to CYP2C192 carriers (Point-of-care genetic screening with subsequent prasugrel administration to CYP2C192 carriers)

Stable Coronary Artery Disease; Acute Coronary Syndrome · Stable Coronary Artery Disease

#StableCoronaryArteryDisease#CGT#Phase3#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleNovartis PharmaceuticalsPhase 3

Previously treated CAR-T patients (Previously treated CAR-T patients)

Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program · Long Term Safety of Patients Receiving C

#LongTermSafetyofPatientsReceivin#CGT#Phase3#cell-gene-therapy#CAR-T+2

Prior MB-102 CAR-T cell investigational product. (Prior MB-102 CAR-T cell investigational product.)

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN); Chronic Lymphocytic Leukemia in Relapse · FRα

Prior MB-106 CAR-T cell investigational product. (Prior MB-106 CAR-T cell investigational product.)

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN); Chronic Lymphocytic Leukemia in Relapse · FRα

CGTAAVLimited DatastaleMeiraGTx UK II LtdPreclinical

Prior exposure to AAV-CNGA3 or AAV-CNGB3 (Prior exposure to AAV-CNGA3 or AAV-CNGB3)

Achromatopsia · Achromatopsia

#Achromatopsia#CGT#Preclinical#cell-gene-therapy#CAR-T+2

CGTLimited DatastaleBeijing GoBroad HospitalPhase 2

Prior-HSCT donor-derived CD7 CAR T-cell (Prior-HSCT donor-derived CD7 CAR T-cell)

T-cell Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia, in Relapse · FRα

#FR#CGT#Phase2#cell-gene-therapy#CAR-T+5

CGTLimited DatastaleFred Hutchinson Cancer CenterPhase 1

ROR1 CAR-specific Autologous T-Lymphocytes (ROR1 CAR-specific Autologous T-Lymphocytes)

Hematopoietic and Lymphoid Cell Neoplasm; Malignant Solid Neoplasm · FRα

#FR#CGT#Phase1#cell-gene-therapy#CAR-T+4

CGTLimited DatastaleReplimune, Inc.Phase 2

RP1, intra-tumoral injection, oncolytic virus (RP1, intra-tumoral injection, oncolytic virus)

Merkel Cell Carcinoma; Basal Cell Carcinoma · Merkel Cell Carcinoma

#MerkelCellCarcinoma#CGT#Phase2#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleEden BioCell Ltd.Phase 1

RPM CD19-mbIL15-CAR-T cells (RPM CD19-mbIL15-CAR-T cells)

B-cell Acute Lymphoblastic Leukemia; Non-Hodgkin's Lymphoma, Relapsed · CD19

#CD19#CGT#Phase1#cell-gene-therapy#CAR-T+5

CGTLimited DatastaleCNBG-Virogin Biotech (Shanghai)…Phase 2

Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell, Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection, Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell)))

Metastatic Gastric Cancer · MET

#MET#CGT#Phase2#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleThe Affiliated Hospital of Xuzh…Phase 1

Recombinant oncolytic adenovirus injection solution of VT-101 (Recombinant oncolytic adenovirus injection solution of VT-101)

Non-muscle Invasive Bladder Cancer · Non-muscle Invasive Bladder Cancer

#Non-muscleInvasiveBladderCancer#CGT#Phase1#cell-gene-therapy#CAR-T+2

CGTLimited DatastaleGuangzhou Virotech Pharmaceutic…Phase 1

Recombinant oncolytic virus M1, anti PD-1 antibody, Apatinib (Recombinant oncolytic virus M1, anti PD-1 antibody, Apatinib)

Advanced/Metastatic Hepatocellular Carcinoma · PD-1

#PD-1#CGT#Phase1#cell-gene-therapy#CAR-T+4

CGTLimited DatastaleDonghua ZhangPreclinical

Recurrent/refractory multiple myeloma (Recurrent/refractory multiple myeloma, Recurrent/refractory multiple myeloma (r/r MM) patients received infusion of BCMA-GPRC5D CAR-T cells, r/r MM)

Multiple Myeloma · BCMA

#BCMA#CGT#Preclinical#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleXinqiao Hospital of ChongqingPhase 1

Retroviral vector-transduced autologous T cells to express CD22-specific CARs (Retroviral vector-transduced autologous T cells to express CD22-specific CARs)

Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Follicular Lymphoma · CD22

#CD22#CGT#Phase1#cell-gene-therapy#CAR-T+4

CGTLimited DatastaleXinqiao Hospital of ChongqingPhase 2

Retroviral vector-transduced autologous T cells to express anti-GPC3 CARs (Retroviral vector-transduced autologous T cells to express anti-GPC3 CARs)

Hepatocellular Carcinoma · Hepatocellular Carcinoma

#HepatocellularCarcinoma#CGT#Phase2#cell-gene-therapy#CAR-T+2

CGTLimited DatastaleChinese PLA General HospitalPhase 2

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Biologic만FDA만

Pan-T booster co-expressing MSLN CAR T cell (Pan-T booster co-expressing MSLN CAR T cell)

Advanced or Metastatic Solid Tumors · Advanced or Metastatic Solid Tumors

#AdvancedorMetastaticSolidTumors#CGT#Phase2#cell-gene-therapy#CAR-T+2

2nd generation T cells (Patient Derived CD171 specific CAR T cells expressing EGFRt, Patient Derived CD171 specific CAR T cells expressing EGFRt (2nd generation T cells))

Neuroblastoma; Ganglioneuroblastoma · EGFR

CGTLimited DatastaleSeattle Children's HospitalPhase 1

3rd generation T cells (Patient Derived CD171 specific CAR T cells expressing EGFRt, Patient Derived CD171 specific CAR T cells expressing EGFRt (3rd generation T cells))

Neuroblastoma; Ganglioneuroblastoma · EGFR

long spacer 2nd generation T cells (Patient Derived CD171 specific CAR T cells expressing EGFRt, Patient Derived CD171 specific CAR T cells expressing EGFRt (long spacer 2nd generation T cells))

Neuroblastoma; Ganglioneuroblastoma · EGFR

CGTLimited DatastalePell Bio-Med Technology Co., Lt…Preclinical

Pell's lentiviral-based gene-edited immune cell therapy (Pell's lentiviral-based gene-edited immune cell therapy)

Diffuse Large B Cell Lymphoma; Large B-cell Lymphoma · Diffuse Large B Cell Lymphoma

#DiffuseLargeBCellLymphoma#CGT#Preclinical#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleOttawa Heart Institute Research…Phase 3

Point-of-care genetic screening with subsequent prasugrel administration to CYP2C192 carriers (Point-of-care genetic screening with subsequent prasugrel administration to CYP2C192 carriers)

Stable Coronary Artery Disease; Acute Coronary Syndrome · Stable Coronary Artery Disease

#StableCoronaryArteryDisease#CGT#Phase3#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleNovartis PharmaceuticalsPhase 3

Previously treated CAR-T patients (Previously treated CAR-T patients)

Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program · Long Term Safety of Patients Receiving C

#LongTermSafetyofPatientsReceivin#CGT#Phase3#cell-gene-therapy#CAR-T+2

Prior MB-102 CAR-T cell investigational product. (Prior MB-102 CAR-T cell investigational product.)

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN); Chronic Lymphocytic Leukemia in Relapse · FRα

Prior MB-106 CAR-T cell investigational product. (Prior MB-106 CAR-T cell investigational product.)

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN); Chronic Lymphocytic Leukemia in Relapse · FRα

CGTAAVLimited DatastaleMeiraGTx UK II LtdPreclinical

Prior exposure to AAV-CNGA3 or AAV-CNGB3 (Prior exposure to AAV-CNGA3 or AAV-CNGB3)

Achromatopsia · Achromatopsia

#Achromatopsia#CGT#Preclinical#cell-gene-therapy#CAR-T+2

CGTLimited DatastaleBeijing GoBroad HospitalPhase 2

Prior-HSCT donor-derived CD7 CAR T-cell (Prior-HSCT donor-derived CD7 CAR T-cell)

T-cell Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia, in Relapse · FRα

#FR#CGT#Phase2#cell-gene-therapy#CAR-T+5

CGTLimited DatastaleFred Hutchinson Cancer CenterPhase 1

ROR1 CAR-specific Autologous T-Lymphocytes (ROR1 CAR-specific Autologous T-Lymphocytes)

Hematopoietic and Lymphoid Cell Neoplasm; Malignant Solid Neoplasm · FRα

#FR#CGT#Phase1#cell-gene-therapy#CAR-T+4

CGTLimited DatastaleReplimune, Inc.Phase 2

RP1, intra-tumoral injection, oncolytic virus (RP1, intra-tumoral injection, oncolytic virus)

Merkel Cell Carcinoma; Basal Cell Carcinoma · Merkel Cell Carcinoma

#MerkelCellCarcinoma#CGT#Phase2#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleEden BioCell Ltd.Phase 1

RPM CD19-mbIL15-CAR-T cells (RPM CD19-mbIL15-CAR-T cells)

B-cell Acute Lymphoblastic Leukemia; Non-Hodgkin's Lymphoma, Relapsed · CD19

#CD19#CGT#Phase1#cell-gene-therapy#CAR-T+5

CGTLimited DatastaleCNBG-Virogin Biotech (Shanghai)…Phase 2

Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell, Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection, Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell)))

Metastatic Gastric Cancer · MET

#MET#CGT#Phase2#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleThe Affiliated Hospital of Xuzh…Phase 1

Recombinant oncolytic adenovirus injection solution of VT-101 (Recombinant oncolytic adenovirus injection solution of VT-101)

Non-muscle Invasive Bladder Cancer · Non-muscle Invasive Bladder Cancer

#Non-muscleInvasiveBladderCancer#CGT#Phase1#cell-gene-therapy#CAR-T+2

CGTLimited DatastaleGuangzhou Virotech Pharmaceutic…Phase 1

Recombinant oncolytic virus M1, anti PD-1 antibody, Apatinib (Recombinant oncolytic virus M1, anti PD-1 antibody, Apatinib)

Advanced/Metastatic Hepatocellular Carcinoma · PD-1

#PD-1#CGT#Phase1#cell-gene-therapy#CAR-T+4

CGTLimited DatastaleDonghua ZhangPreclinical

Recurrent/refractory multiple myeloma (Recurrent/refractory multiple myeloma, Recurrent/refractory multiple myeloma (r/r MM) patients received infusion of BCMA-GPRC5D CAR-T cells, r/r MM)

Multiple Myeloma · BCMA

#BCMA#CGT#Preclinical#cell-gene-therapy#CAR-T+3

CGTLimited DatastaleXinqiao Hospital of ChongqingPhase 1

Retroviral vector-transduced autologous T cells to express CD22-specific CARs (Retroviral vector-transduced autologous T cells to express CD22-specific CARs)

Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Follicular Lymphoma · CD22

#CD22#CGT#Phase1#cell-gene-therapy#CAR-T+4

CGTLimited DatastaleXinqiao Hospital of ChongqingPhase 2

Retroviral vector-transduced autologous T cells to express anti-GPC3 CARs (Retroviral vector-transduced autologous T cells to express anti-GPC3 CARs)

Hepatocellular Carcinoma · Hepatocellular Carcinoma

#HepatocellularCarcinoma#CGT#Phase2#cell-gene-therapy#CAR-T+2