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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일

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API CSV14행 · 1개 프로그램
OverviewToxicologyClinical

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항목
AntibodyLimited DatastalePhase 2
vadastuximab talirine (vadastuximab talirine)
Seagen Inc.·Myelodysplastic Syndrome
5 trials
Overview
Program
vadastuximab talirine
Overview
Company
Seagen Inc.
Overview
Modality
ANTIBODY
Overview
Target
Myelodysplastic Syndrome
Overview
Indication
Myelodysplastic Syndrome
Overview
Phase
PHASE_2
Overview
Status
DISCONTINUED
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML.. Treatment of acute myeloid leukemia (AML) among the elderly is challenging because of intolerance of intensive therapy and therapy-resistant biology. Hypomethylating agents (HMAs) are commonly used, with suboptimal outcomes. Vadastuximab talirine is a CD33-directed antibody conjugated…
Clinical
Safety signal
A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML.. Treatment of acute myeloid leukemia (AML) among the elderly is challenging because of intolerance of intensive therapy and therapy-resistant biology. Hypomethylating agents (HMAs) are commonly used, with suboptimal outcomes. Vadastuximab talirine is a CD33-directed antibody conjugated…
Clinical
Program phase
PHASE_2