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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일

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항목
CGTStandard DatabasestalePhase 2
Activated NK Cells (M-CENK, M-CENK (Activated NK Cells))
ImmunityBio, Inc.·High-risk Prostate Cancer
59 trials
Overview
Program
M-CENK (Activated NK Cells)
Overview
Company
ImmunityBio, Inc.
Overview
Modality
CGT
Overview
Target
High-risk Prostate Cancer
Overview
Indication
High-risk Prostate Cancer
Overview
Phase
PHASE_2
Overview
Status
DISCONTINUED
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Technology
Vector
viral vectors can further confine scFv activity to tumors, coupling checkpoint blockade with
MoA
Mechanism
target of rapamycin (mTOR) pathway
MoA
Biomarker
biomarkers and dynamic metabolic monitoring may support patient stratification and response prediction
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
hepatotoxicity and variable patient responses remain challenges
Toxicology
CRS
Reported
Clinical
Safety signal
hepatotoxicity and variable patient responses remain challenges
Clinical
Reported OS
94.4
Clinical
Result source
ClinicalTrials.gov NCT01700946
Clinical
Program phase
PHASE_2
Clinical
Trial ref
NCT01700946