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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일

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API CSV18행 · 1개 프로그램

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항목
AntibodyLimited DatastalePhase 1
pembrolizumab (Keytruda, Letetresgene autoleucel with pembrolizumab)
Merck·Neoplasms
2 trials
Overview
Program
Letetresgene autoleucel with pembrolizumab
Overview
Company
Merck
Overview
Modality
ANTIBODY
Overview
Target
Neoplasms
Overview
Indication
Neoplasms
Overview
Phase
PHASE_1
Overview
Status
DISCONTINUED
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
Toxicology
Major finding
Safety and Tolerability of Letetresgene Autoleucel (GSK3377794): Pilot Studies in Patients with Advanced Non-Small Cell Lung Cancer.. The study aims to evaluate the safety, tolerability, and antitumor response of letetresgene autoleucel (lete-cel), genetically modified autologous T cells expressing a T-cell receptor specific for New York esophageal squamous cell carcinoma 1 (NY-ESO-1)/LAGE-1a shar…
Toxicology
CRS
Reported
Clinical
Safety signal
Safety and Tolerability of Letetresgene Autoleucel (GSK3377794): Pilot Studies in Patients with Advanced Non-Small Cell Lung Cancer.. The study aims to evaluate the safety, tolerability, and antitumor response of letetresgene autoleucel (lete-cel), genetically modified autologous T cells expressing a T-cell receptor specific for New York esophageal squamous cell carcinoma 1 (NY-ESO-1)/LAGE-1a shar…
Clinical
Reported ORR
0%
Clinical
Result source
ClinicalTrials.gov NCT03709706
Clinical
Program phase
PHASE_1
Clinical
Trial ref
NCT03709706