구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Lenzilumab |
Overview Company | Kite, A Gilead Company |
Overview Modality | ANTIBODY |
Overview Target | FRα |
Overview Indication | Relapsed/Refractory Large B-cell Lymphoma |
Overview Phase | PHASE_1 |
Overview Status | DISCONTINUED |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Watch |
Overview Approval status | Investigational |
Toxicology Major finding | Pharmacokinetics, Safety and Tolerability of Intravenous Lenzilumab, an Anti-GM-CSF Monoclonal Antibody Drug, in Healthy Korean Subjects.. Lenzilumab is a recombinant monoclonal antibody neutralizing human granulocyte macrophage-colony stimulating factor. By modulating proinflammatory cytokine cascade, lenzilumab is expected to be effective in prevention and treatment of cytokine release syndrome.… |
Toxicology CRS | Reported |
Clinical Safety signal | Pharmacokinetics, Safety and Tolerability of Intravenous Lenzilumab, an Anti-GM-CSF Monoclonal Antibody Drug, in Healthy Korean Subjects.. Lenzilumab is a recombinant monoclonal antibody neutralizing human granulocyte macrophage-colony stimulating factor. By modulating proinflammatory cytokine cascade, lenzilumab is expected to be effective in prevention and treatment of cytokine release syndrome.… |
Clinical Selected reported efficacy | ORR 9.9% |
Clinical Reported ORR | 9.9% |
Clinical Result source | ClinicalTrials.gov NCT04314843 |
Clinical Program phase | PHASE_1 |
Clinical Trial ref | NCT04314843 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Lenzilumab |
Overview Company | Kite, A Gilead Company |
Overview Modality | ANTIBODY |
Overview Target | FRα |
Overview Indication | Relapsed/Refractory Large B-cell Lymphoma |
Overview Phase | PHASE_1 |
Overview Status | DISCONTINUED |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Watch |
Overview Approval status | Investigational |
Toxicology Major finding | Pharmacokinetics, Safety and Tolerability of Intravenous Lenzilumab, an Anti-GM-CSF Monoclonal Antibody Drug, in Healthy Korean Subjects.. Lenzilumab is a recombinant monoclonal antibody neutralizing human granulocyte macrophage-colony stimulating factor. By modulating proinflammatory cytokine cascade, lenzilumab is expected to be effective in prevention and treatment of cytokine release syndrome.… |
Toxicology CRS | Reported |
Clinical Safety signal | Pharmacokinetics, Safety and Tolerability of Intravenous Lenzilumab, an Anti-GM-CSF Monoclonal Antibody Drug, in Healthy Korean Subjects.. Lenzilumab is a recombinant monoclonal antibody neutralizing human granulocyte macrophage-colony stimulating factor. By modulating proinflammatory cytokine cascade, lenzilumab is expected to be effective in prevention and treatment of cytokine release syndrome.… |
Clinical Selected reported efficacy | ORR 9.9% |
Clinical Reported ORR | 9.9% |
Clinical Result source | ClinicalTrials.gov NCT04314843 |
Clinical Program phase | PHASE_1 |
Clinical Trial ref | NCT04314843 |
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