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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일

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항목
AntibodyLimited DatastalePhase 2
pembrolizumab (Keytruda, Coformulated favezelimab/pembrolizumab)
Merck·Metastatic Urothelial Carcinoma
6 trials
Overview
Program
Coformulated favezelimab/pembrolizumab
Overview
Company
Merck
Overview
Modality
ANTIBODY
Overview
Target
Metastatic Urothelial Carcinoma
Overview
Indication
Metastatic Urothelial Carcinoma; Urothelial Neoplasms
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer.. Treatment options are limited for participants with microsatellite stable (MSS) metastatic colorectal cancer (mCRC) that progressed after two or more prior therapies. Studies have shown that blockade of both lymphocyte-activation gene 3 (LAG-3) …
Clinical
Safety signal
A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer.. Treatment options are limited for participants with microsatellite stable (MSS) metastatic colorectal cancer (mCRC) that progressed after two or more prior therapies. Studies have shown that blockade of both lymphocyte-activation gene 3 (LAG-3) …
Clinical
Selected reported efficacy
ORR 6.8%
Clinical
Reported ORR
6.8%
Clinical
Result source
ClinicalTrials.gov NCT05064059
Clinical
Program phase
PHASE_2
Clinical
Trial ref
NCT05064059