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항목
AntibodyLimited DatastalePhase 2
Acetaminophen (Acetaminophen)
Janssen Research & Development, LL…·Lymphoma, Non-Hodgkin
135 trials
Overview
Program
Acetaminophen
Overview
Company
Janssen Research & Development, LLC
Overview
Modality
ANTIBODY
Overview
Target
Lymphoma, Non-Hodgkin
Overview
Indication
Pompe Disease
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
MoA
Mechanism
remains incompletely understood
MoA
Biomarker
biomarker analyses indicated significant changes in 1) esterase activity (60
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
pharmacokinetic
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
hepatotoxicity testing remains unclear
Toxicology
CRS
Reported
Clinical
Safety signal
hepatotoxicity testing remains unclear
Clinical
Selected reported efficacy
ORR 70.5%
Clinical
Reported ORR
70.5%
Clinical
Result source
ClinicalTrials.gov NCT05405166
Clinical
Program phase
PHASE_2
Clinical
Trial activity
No active/completed counts
Clinical
Trial ref
NCT05405166