구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Total Body Irradiation (TBI, Total Body Irradiation, Total Body Irradiation (TBI) (Plan 1)) Swedish Orphan Biovitrum·Fanconi Anemia 214 trials |
|---|---|
Overview Program | Total Body Irradiation (TBI) (Plan 1) |
Overview Company | Swedish Orphan Biovitrum |
Overview Modality | ANTIBODY |
Overview Target | Fanconi Anemia |
Overview Indication | Fanconi Anemia; Severe Aplastic Anemia |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | targets within steroid hormone pathway |
MoA Biomarker | biomarkers will be essential to fully realize the neuroprotective and neuroregenerative potential of neurotro |
PK/PD Species | Rabbit |
PK/PD Animal (cat.) | Unknown |
PK/PD Experiment | PD |
Toxicology Species | Rabbit |
Toxicology Animal (cat.) | Unknown |
Toxicology Major finding | Time-dependent immune and skeletal alterations following total-body irradiation and hematopoietic stem cell transplantation in a murine arthritis model.. Hematopoietic stem cell transplantation (HSCT) after cytotoxic conditioning, such as total-body irradiation (TBI), is widely used to treat hematologic and immune disorders. However, this treatment is associated with long-term systemic effects, in… |
Clinical Safety signal | Time-dependent immune and skeletal alterations following total-body irradiation and hematopoietic stem cell transplantation in a murine arthritis model.. Hematopoietic stem cell transplantation (HSCT) after cytotoxic conditioning, such as total-body irradiation (TBI), is widely used to treat hematologic and immune disorders. However, this treatment is associated with long-term systemic effects, in… |
Clinical Selected reported efficacy | 25% |
Clinical Result source | ClinicalTrials.gov NCT00119392 |
Clinical Program phase | PHASE_2 |
Clinical Trial activity | No active/completed counts |
Clinical Trial ref | NCT00119392 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Total Body Irradiation (TBI, Total Body Irradiation, Total Body Irradiation (TBI) (Plan 1)) Swedish Orphan Biovitrum·Fanconi Anemia 214 trials |
|---|---|
Overview Program | Total Body Irradiation (TBI) (Plan 1) |
Overview Company | Swedish Orphan Biovitrum |
Overview Modality | ANTIBODY |
Overview Target | Fanconi Anemia |
Overview Indication | Fanconi Anemia; Severe Aplastic Anemia |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | targets within steroid hormone pathway |
MoA Biomarker | biomarkers will be essential to fully realize the neuroprotective and neuroregenerative potential of neurotro |
PK/PD Species | Rabbit |
PK/PD Animal (cat.) | Unknown |
PK/PD Experiment | PD |
Toxicology Species | Rabbit |
Toxicology Animal (cat.) | Unknown |
Toxicology Major finding | Time-dependent immune and skeletal alterations following total-body irradiation and hematopoietic stem cell transplantation in a murine arthritis model.. Hematopoietic stem cell transplantation (HSCT) after cytotoxic conditioning, such as total-body irradiation (TBI), is widely used to treat hematologic and immune disorders. However, this treatment is associated with long-term systemic effects, in… |
Clinical Safety signal | Time-dependent immune and skeletal alterations following total-body irradiation and hematopoietic stem cell transplantation in a murine arthritis model.. Hematopoietic stem cell transplantation (HSCT) after cytotoxic conditioning, such as total-body irradiation (TBI), is widely used to treat hematologic and immune disorders. However, this treatment is associated with long-term systemic effects, in… |
Clinical Selected reported efficacy | 25% |
Clinical Result source | ClinicalTrials.gov NCT00119392 |
Clinical Program phase | PHASE_2 |
Clinical Trial activity | No active/completed counts |
Clinical Trial ref | NCT00119392 |
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