구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Tiragolumab |
Overview Company | Genentech, Inc. |
Overview Modality | ANTIBODY |
Overview Target | Urothelial Carcinoma |
Overview Indication | Multiple Myeloma; Non-Hodgkin Lymphoma |
Overview Phase | PHASE_3 |
Overview Status | ACTIVE |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | of anti-TIGIT antibodies as monotherapy or in combination with anti-programmed cell death protein-1 (PD-1) antibody in vivo by gene expression profiling and flow cytometry analyses with a mouse syngeneic tumor model |
MoA Biomarker | PD-L1-positive |
PK/PD Species | Mouse |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | PD |
Toxicology Species | Mouse |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | pneumonitis, cardiac arrest, gastrointestinal haemorrhage, hepatic failure, and bacterial p |
Clinical Safety signal | pneumonitis, cardiac arrest, gastrointestinal haemorrhage, hepatic failure, and bacterial p |
Clinical Selected reported efficacy | ORR 77.3% |
Clinical Reported ORR | 59.1% |
Clinical Reported PFS | 2.07 |
Clinical Reported OS | NA |
Clinical Result source | ClinicalTrials.gov NCT05116202 |
Clinical Program phase | PHASE_3 |
Clinical Trial activity | No active/completed counts |
Clinical Trial ref | NCT05116202 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Tiragolumab |
Overview Company | Genentech, Inc. |
Overview Modality | ANTIBODY |
Overview Target | Urothelial Carcinoma |
Overview Indication | Multiple Myeloma; Non-Hodgkin Lymphoma |
Overview Phase | PHASE_3 |
Overview Status | ACTIVE |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | of anti-TIGIT antibodies as monotherapy or in combination with anti-programmed cell death protein-1 (PD-1) antibody in vivo by gene expression profiling and flow cytometry analyses with a mouse syngeneic tumor model |
MoA Biomarker | PD-L1-positive |
PK/PD Species | Mouse |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | PD |
Toxicology Species | Mouse |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | pneumonitis, cardiac arrest, gastrointestinal haemorrhage, hepatic failure, and bacterial p |
Clinical Safety signal | pneumonitis, cardiac arrest, gastrointestinal haemorrhage, hepatic failure, and bacterial p |
Clinical Selected reported efficacy | ORR 77.3% |
Clinical Reported ORR | 59.1% |
Clinical Reported PFS | 2.07 |
Clinical Reported OS | NA |
Clinical Result source | ClinicalTrials.gov NCT05116202 |
Clinical Program phase | PHASE_3 |
Clinical Trial activity | No active/completed counts |
Clinical Trial ref | NCT05116202 |
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