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항목
ADCLimited DatastalePhase 2
Taxotere (Taxotere)
Spanish Breast Cancer Research Gro…·Metastatic Breast Cancer
127 trials
Overview
Program
Taxotere
Overview
Company
Spanish Breast Cancer Research Group
Overview
Modality
ADC
Overview
Target
Metastatic Breast Cancer
Overview
Indication
Metastatic Breast Cancer
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Technology
Linker
linker length adjacent to the disulfide bond
MoA
Mechanism
targeted therapy of Human Epidermal Growth Factor Receptor
MoA
Biomarker
biomarkers have been found that effectively forecast the prognosis of patients suffering from PAAD
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Human, Mouse, In vitro
PK/PD
Experiment
pharmacokinetic
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Human, Mouse, In vitro
Toxicology
Major finding
hepatotoxicity caused by doxorubicin, Taxotere, and PD98059 mono/combination therapy in a h
Clinical
Safety signal
hepatotoxicity caused by doxorubicin, Taxotere, and PD98059 mono/combination therapy in a h
Clinical
Selected reported efficacy
ORR 22.7%
Clinical
Reported ORR
22.7%
Clinical
Result source
ClinicalTrials.gov NCT03976375
Clinical
Program phase
PHASE_2
Clinical
Trial activity
No active/completed counts
Clinical
Trial ref
NCT03976375
Taxotere 비교 | 바이오정보모아