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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일

현재 선택: 1 · 임상 갱신 필요 1

프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.

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항목
CGTStandard DatabasestalePhase 2
allogeneic Natural Killer cell ('SMT-NK' Inj, 'SMT-NK' Inj (allogeneic Natural Killer cell))
SMT bio Co., Ltd.·Biliary Tract Cancer
58 trials
Overview
Program
'SMT-NK' Inj (allogeneic Natural Killer cell)
Overview
Company
SMT bio Co., Ltd.
Overview
Modality
CGT
Overview
Target
Biliary Tract Cancer
Overview
Indication
Biliary Tract Cancer
Overview
Phase
PHASE_2
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
MoA
Mechanism
targeting and cytotoxicity by coupling NK cells with tumor-specific antibodies targeting antigen
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
thrombocytopenia and neutropenia
Toxicology
CRS
Reported
Clinical
Safety signal
thrombocytopenia and neutropenia
Clinical
Reported PFS
10
Clinical
Reported OS
11
Clinical
Result source
ClinicalTrials.gov NCT02100891
Clinical
Program phase
PHASE_2
Clinical
Trial ref
NCT02100891
Preclinical
Animal (cat.)
Mouse, In vitro