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항목
ADCLimited DatastalePhase 2
Prednisolone (Prednisolone)
Genentech, Inc.·Solid Tumor
160 trials
Overview
Program
Prednisolone
Overview
Company
Genentech, Inc.
Overview
Modality
ADC
Overview
Target
Solid Tumor
Overview
Indication
Lymphoma, Large B-Cell, Diffuse
Overview
Phase
PHASE_2
Overview
Status
ACTIVE
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
MoA
Mechanism
target genes of antipsychotic drugs are mainly enriched in cellular response to dopamine, phospholipase C-activating G protein-coupled receptor signaling pathway
MoA
Biomarker
Biomarker in Acute Bell's Palsy: A Prospective Cohort Study
PK/PD
Species
Dog
PK/PD
Animal (cat.)
Dog
PK/PD
Experiment
PD
Toxicology
Species
Dog
Toxicology
Animal (cat.)
Dog
Toxicology
Major finding
pneumonitis with high serum and bronchoalveolar viral loads, herpesvirus reactivation compa
Toxicology
CRS
Reported
Clinical
Safety signal
pneumonitis with high serum and bronchoalveolar viral loads, herpesvirus reactivation compa
Clinical
Selected reported efficacy
ORR 85.5%
Clinical
Reported ORR
85.5%
Clinical
Reported PFS
32.9
Clinical
Reported OS
NA
Clinical
Result source
ClinicalTrials.gov NCT02626455
Clinical
Program phase
PHASE_2
Clinical
Trial activity
No active/completed counts
Clinical
Trial ref
NCT02626455