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항목
ADCStandard DatabasestalePreclinical
Pneumococcal Conjugate Vaccine, Heptavalent (Pneumococcal Conjugate Vaccine, Heptavalent)
Sanofi Pasteur, a Sanofi Company·HIV Infections
52 trials·t½ 12 h
Overview
Program
Pneumococcal Conjugate Vaccine, Heptavalent
Overview
Company
Sanofi Pasteur, a Sanofi Company
Overview
Modality
ADC
Overview
Target
HIV Infections
Overview
Indication
HIV Infections; Hepatitis B
Overview
Phase
PRECLINICAL
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
PK/PD
Half-life
12 h
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
A phase 3, multicenter, randomized, double-blind, active-comparator-controlled study to evaluate the safety, tolerability, and immunogenicity of a 4-dose regimen of V114, a 15-valent pneumococcal conjugate vaccine, in healthy infants (PNEU-PED).. Pneumococcal disease (PD) remains a major health concern with considerable morbidity and mortality in children. Currently licensed pneumococcal conjugate…
Clinical
Safety signal
A phase 3, multicenter, randomized, double-blind, active-comparator-controlled study to evaluate the safety, tolerability, and immunogenicity of a 4-dose regimen of V114, a 15-valent pneumococcal conjugate vaccine, in healthy infants (PNEU-PED).. Pneumococcal disease (PD) remains a major health concern with considerable morbidity and mortality in children. Currently licensed pneumococcal conjugate…
Clinical
Selected reported efficacy
1%
Clinical
Result source
ClinicalTrials.gov NCT01307449
Clinical
Program phase
PRECLINICAL
Clinical
Trial ref
NCT01307449