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항목
ADCStandard DatabasestalePhase 2
Pinatuzumab Vedotin (Pinatuzumab Vedotin)
Genentech, Inc.·Follicular Lymphoma
2 trials
Overview
Program
Pinatuzumab Vedotin
Overview
Company
Genentech, Inc.
Overview
Modality
ADC
Overview
Target
Follicular Lymphoma
Overview
Indication
Follicular Lymphoma; Diffuse Large B-Cell Lymphoma
Overview
Phase
PHASE_2
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
Polatuzumab vedotin or pinatuzumab vedotin plus rituximab in patients with relapsed or refractory non-Hodgkin lymphoma: final results from a phase 2 randomised study (ROMULUS).. Antibody-drug conjugates (ADCs) polatuzumab vedotin (pola) and pinatuzumab vedotin (pina) showed clinical activity and tolerability in phase 1 trials. The aim of this multicentre, open-label, phase 2 study was to compare r…
Clinical
Safety signal
Polatuzumab vedotin or pinatuzumab vedotin plus rituximab in patients with relapsed or refractory non-Hodgkin lymphoma: final results from a phase 2 randomised study (ROMULUS).. Antibody-drug conjugates (ADCs) polatuzumab vedotin (pola) and pinatuzumab vedotin (pina) showed clinical activity and tolerability in phase 1 trials. The aim of this multicentre, open-label, phase 2 study was to compare r…
Clinical
Selected reported efficacy
ORR 6.24%
Clinical
Reported ORR
6.24%
Clinical
Result source
ClinicalTrials.gov NCT01691898
Clinical
Program phase
PHASE_2
Clinical
Trial ref
NCT01691898