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API CSV22행 · 1개 프로그램

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항목
AntibodyCurated CorestaleApproved
Ixekizumab (Ixekizumab)
Eli Lilly and Company·Psoriatic Arthritis
53 trials·t½ 13 h
Overview
Program
Ixekizumab
Overview
Company
Eli Lilly and Company
Overview
Modality
ANTIBODY
Overview
Target
Psoriatic Arthritis
Overview
Indication
Psoriasis; Atopic Dermatitis
Overview
Phase
APPROVED
Overview
Status
RECRUITING
Overview
Content status
Curated Core
Overview
Data Confidence
Data Confidence · High
Overview
Development Signal
Development Signal · Established
Overview
Approval status
Approved (flag incomplete)
Positioning
Key differentiator
Novel approaches, including tolerogenic DC therapy and neuroimmune modulation, hold promise for refining treatment and addres
MoA
Mechanism
targets and signaling pathway
PK/PD
Half-life
13 h
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
pharmacokinetic
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
Ixekizumab Treatment Persistence in Psoriatic Arthritis: Response to Joaquin et al.. We appreciate the interest of Joaquin et al in our recent study on the treatment persistence of ixekizumab in psoriatic arthritis. In response, we clarify that our study utilized prospectively collected real-world clinical data from a multicenter observational cohort, rather than administrative databases. We empha…
Clinical
Safety signal
Ixekizumab Treatment Persistence in Psoriatic Arthritis: Response to Joaquin et al.. We appreciate the interest of Joaquin et al in our recent study on the treatment persistence of ixekizumab in psoriatic arthritis. In response, we clarify that our study utilized prospectively collected real-world clinical data from a multicenter observational cohort, rather than administrative databases. We empha…
Clinical
Program phase
APPROVED