구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | oncolytic vaccinia virus (IDOV-Immune, IDOV-Immune (oncolytic vaccinia virus)) ViroMissile, Inc.·Colorectal Cancer 40 trials |
|---|---|
Overview Program | IDOV-Immune (oncolytic vaccinia virus) |
Overview Company | ViroMissile, Inc. |
Overview Modality | CGT |
Overview Target | Colorectal Cancer |
Overview Indication | Colorectal Cancer; Pancreatic Cancer |
Overview Phase | PHASE_1 |
Overview Status | RECRUITING |
Overview Content status | Standard Database |
Overview Data Confidence | Data Confidence · Medium |
Overview Development Signal | Development Signal · Watch |
Overview Approval status | Investigational |
Technology Vector | viral vector platforms |
MoA Mechanism | targeting the programmed cell death protein-1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway |
MoA Biomarker | PD-1-directed IL-2 expression |
PK/PD Species | Dog |
PK/PD Animal (cat.) | Dog, In vitro |
PK/PD Experiment | PD |
Toxicology Species | Dog |
Toxicology Animal (cat.) | Dog, In vitro |
Toxicology Major finding | Oncolytic Viruses for Cancer Therapy in Dogs.. Cancer remains the leading cause of death in domestic dogs. Conventional therapeutic approaches, including surgery, chemotherapy, and radiotherapy, frequently fail to achieve sustained remission or stabilization. Oncolytic virotherapy, a rapidly advancing therapeutic modality in human oncology, is emerging as a novel strategy in veterinary medicine. T… |
Clinical Safety signal | Oncolytic Viruses for Cancer Therapy in Dogs.. Cancer remains the leading cause of death in domestic dogs. Conventional therapeutic approaches, including surgery, chemotherapy, and radiotherapy, frequently fail to achieve sustained remission or stabilization. Oncolytic virotherapy, a rapidly advancing therapeutic modality in human oncology, is emerging as a novel strategy in veterinary medicine. T… |
Clinical Selected reported efficacy | ORR 80% |
Clinical Reported ORR | 80.0% |
Clinical Reported PFS | 10 |
Clinical Reported OS | 33.6 |
Clinical Result source | ClinicalTrials.gov NCT02759588 |
Clinical Program phase | PHASE_1 |
Clinical Trial ref | NCT02759588 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | oncolytic vaccinia virus (IDOV-Immune, IDOV-Immune (oncolytic vaccinia virus)) ViroMissile, Inc.·Colorectal Cancer 40 trials |
|---|---|
Overview Program | IDOV-Immune (oncolytic vaccinia virus) |
Overview Company | ViroMissile, Inc. |
Overview Modality | CGT |
Overview Target | Colorectal Cancer |
Overview Indication | Colorectal Cancer; Pancreatic Cancer |
Overview Phase | PHASE_1 |
Overview Status | RECRUITING |
Overview Content status | Standard Database |
Overview Data Confidence | Data Confidence · Medium |
Overview Development Signal | Development Signal · Watch |
Overview Approval status | Investigational |
Technology Vector | viral vector platforms |
MoA Mechanism | targeting the programmed cell death protein-1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway |
MoA Biomarker | PD-1-directed IL-2 expression |
PK/PD Species | Dog |
PK/PD Animal (cat.) | Dog, In vitro |
PK/PD Experiment | PD |
Toxicology Species | Dog |
Toxicology Animal (cat.) | Dog, In vitro |
Toxicology Major finding | Oncolytic Viruses for Cancer Therapy in Dogs.. Cancer remains the leading cause of death in domestic dogs. Conventional therapeutic approaches, including surgery, chemotherapy, and radiotherapy, frequently fail to achieve sustained remission or stabilization. Oncolytic virotherapy, a rapidly advancing therapeutic modality in human oncology, is emerging as a novel strategy in veterinary medicine. T… |
Clinical Safety signal | Oncolytic Viruses for Cancer Therapy in Dogs.. Cancer remains the leading cause of death in domestic dogs. Conventional therapeutic approaches, including surgery, chemotherapy, and radiotherapy, frequently fail to achieve sustained remission or stabilization. Oncolytic virotherapy, a rapidly advancing therapeutic modality in human oncology, is emerging as a novel strategy in veterinary medicine. T… |
Clinical Selected reported efficacy | ORR 80% |
Clinical Reported ORR | 80.0% |
Clinical Reported PFS | 10 |
Clinical Reported OS | 33.6 |
Clinical Result source | ClinicalTrials.gov NCT02759588 |
Clinical Program phase | PHASE_1 |
Clinical Trial ref | NCT02759588 |
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