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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일

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API CSV18행 · 1개 프로그램

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항목
AntibodyLimited DatastalePhase 2
Icrucumab (Icrucumab)
Eli Lilly and Company·Carcinoma of Urinary Tract
4 trials
Overview
Program
Icrucumab
Overview
Company
Eli Lilly and Company
Overview
Modality
ANTIBODY
Overview
Target
Carcinoma of Urinary Tract
Overview
Indication
Colon Cancer; Rectal Cancer
Overview
Phase
PHASE_2
Overview
Status
ACTIVE
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
Randomized Phase II Study of Ramucirumab or Icrucumab in Combination with Capecitabine in Patients with Previously Treated Locally Advanced or Metastatic Breast Cancer.. Icrucumab (ICR) and ramucirumab (RAM) bind vascular endothelial growth factor (VEGF) receptors 1 and 2 (VEGFR-1 and -2), respectively. This open-label, randomized phase II study evaluated their efficacy and safety in combination w…
Clinical
Safety signal
Randomized Phase II Study of Ramucirumab or Icrucumab in Combination with Capecitabine in Patients with Previously Treated Locally Advanced or Metastatic Breast Cancer.. Icrucumab (ICR) and ramucirumab (RAM) bind vascular endothelial growth factor (VEGF) receptors 1 and 2 (VEGFR-1 and -2), respectively. This open-label, randomized phase II study evaluated their efficacy and safety in combination w…
Clinical
Selected reported efficacy
ORR 28.8%
Clinical
Reported ORR
28.8%
Clinical
Result source
ClinicalTrials.gov NCT01234402
Clinical
Program phase
PHASE_2
Clinical
Trial ref
NCT01234402