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항목
CGTStandard DatabasestalePreclinical
Genetically engineered NK cells (Genetically engineered NK cells)
Fate Therapeutics·Hematological Malignancy
17 trials
Overview
Program
Genetically engineered NK cells
Overview
Company
Fate Therapeutics
Overview
Modality
CGT
Overview
Target
Hematological Malignancy
Overview
Indication
Hematological Malignancy
Overview
Phase
PRECLINICAL
Overview
Status
DISCONTINUED
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
Toxicology
Major finding
Secretory TRAIL-Armed Natural Killer Cell-Based Therapy: In Vitro and In Vivo Colorectal Peritoneal Carcinomatosis Xenograft.. Since its discovery in 1995, TNF-related apoptosis-inducing ligand (TRAIL) has sparked growing interest among oncologists due to its remarkable ability to induce apoptosis in malignant human cells, but not in most normal cells. However, one major drawback is its fast clear…
Clinical
Safety signal
Secretory TRAIL-Armed Natural Killer Cell-Based Therapy: In Vitro and In Vivo Colorectal Peritoneal Carcinomatosis Xenograft.. Since its discovery in 1995, TNF-related apoptosis-inducing ligand (TRAIL) has sparked growing interest among oncologists due to its remarkable ability to induce apoptosis in malignant human cells, but not in most normal cells. However, one major drawback is its fast clear…
Clinical
Reported ORR
0%
Clinical
Result source
ClinicalTrials.gov NCT03056339
Clinical
Program phase
PRECLINICAL
Clinical
Trial ref
NCT03056339