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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일

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항목
CGTStandard DatabasestalePhase 1
EpCAM CAR-T cells (EpCAM CAR-T cells)
Sichuan University·Malignant Neoplasm of Nasopharynx …
7 trials
Overview
Program
EpCAM CAR-T cells
Overview
Company
Sichuan University
Overview
Modality
CGT
Overview
Target
Malignant Neoplasm of Nasopharynx TNM St
Overview
Indication
Malignant Neoplasm of Nasopharynx TNM Staging Distant Metastasis (M); Breast Cancer Recurrent
Overview
Phase
PHASE_1
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
Toxicology
Major finding
EpCAM-targeting CAR-T cell immunotherapy is safe and efficacious for epithelial tumors.. The efficacy of CAR-T cells for solid tumors is unsatisfactory. EpCAM is a biomarker of epithelial tumors, but the clinical feasibility of CAR-T therapy targeting EpCAM is lacking. Here, we report pre- and clinical investigations of EpCAM-CAR-T cells for solid tumors. We demonstrated that EpCAM-CAR-T cells cos…
Toxicology
CRS
Reported
Clinical
Safety signal
EpCAM-targeting CAR-T cell immunotherapy is safe and efficacious for epithelial tumors.. The efficacy of CAR-T cells for solid tumors is unsatisfactory. EpCAM is a biomarker of epithelial tumors, but the clinical feasibility of CAR-T therapy targeting EpCAM is lacking. Here, we report pre- and clinical investigations of EpCAM-CAR-T cells for solid tumors. We demonstrated that EpCAM-CAR-T cells cos…
Clinical
Program phase
PHASE_1