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항목
AntibodyLimited DatastalePhase 2
Envafolimab (Envafolimab)
3D Medicines (Sichuan) Co., Ltd.·Prostate Cancer
52 trials
Overview
Program
Envafolimab
Overview
Company
3D Medicines (Sichuan) Co., Ltd.
Overview
Modality
ANTIBODY
Overview
Target
Prostate Cancer
Overview
Indication
Prostate Cancer; CDK12 Gene Mutation
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Limited Data
Overview
Data Confidence
Data Confidence · Low
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
MoA
Mechanism
of envafolimab (also known as KN035), a programmed death ligand 1 (PD-L1) inhibitor, in gastric adenocarcinoma patients with low PD-L1 expression is not well understood
MoA
Biomarker
PD-L1)-positive
PK/PD
Species
Mouse, Human
PK/PD
Animal (cat.)
Human, Mouse
PK/PD
Experiment
PD
Toxicology
Species
Mouse, Human
Toxicology
Animal (cat.)
Human, Mouse
Toxicology
Major finding
pneumonitis induced by envafolimab treatment in small cell lung cancer
Clinical
Safety signal
pneumonitis induced by envafolimab treatment in small cell lung cancer
Clinical
Program phase
PHASE_2