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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일

현재 선택: 1 · 임상 갱신 필요 1

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항목
CGTStandard DatabasestalePhase 1
EGFRvIII-CARs (EGFRvIII-CARs)
Gary Archer Ph.D.·EGFR
1 trials
Overview
Program
EGFRvIII-CARs
Overview
Company
Gary Archer Ph.D.
Overview
Modality
CGT
Overview
Target
EGFR
Overview
Indication
Recurrent Glioblastoma; Recurrent Gliosarcoma
Overview
Phase
PHASE_1
Overview
Status
DISCONTINUED
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
Toxicology
Major finding
Application of blood brain barrier models in pre-clinical assessment of glioblastoma-targeting CAR-T based immunotherapies.. Human blood brain barrier (BBB) models derived from induced pluripotent stem cells (iPSCs) have become an important tool for the discovery and preclinical evaluation of central nervous system (CNS) targeting cell and gene-based therapies. Chimeric antigen receptor (CAR)…
Clinical
Safety signal
Application of blood brain barrier models in pre-clinical assessment of glioblastoma-targeting CAR-T based immunotherapies.. Human blood brain barrier (BBB) models derived from induced pluripotent stem cells (iPSCs) have become an important tool for the discovery and preclinical evaluation of central nervous system (CNS) targeting cell and gene-based therapies. Chimeric antigen receptor (CAR)…
Clinical
Result source
ClinicalTrials.gov NCT01454596
Clinical
Program phase
PHASE_1
Clinical
Trial ref
NCT01454596
EGFRvIII-CARs 비교 | 바이오정보모아