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항목
CGTStandard DatabasestalePhase 2
DLL3-CAR-NK cells (DLL3-CAR-NK cells)
Beijing Biotech·SCLC, Extensive Stage
4 trials
Overview
Program
DLL3-CAR-NK cells
Overview
Company
Beijing Biotech
Overview
Modality
CGT
Overview
Target
SCLC, Extensive Stage
Overview
Indication
Extensive Stage Lung Small Cell Cancer
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
CAR NK-92 cells targeting DLL3 kill effectively small cell lung cancer cells in vitro and in vivo.. Small cell lung cancer (SCLC) is characterized by a high relapse rate, drug tolerance, and limited treatment choices. Chimeric antigen receptor (CAR)-modified NK cells represent a promising immunotherapeutic modality for cancer treatment. However, their potential applications have not been explored …
Clinical
Safety signal
CAR NK-92 cells targeting DLL3 kill effectively small cell lung cancer cells in vitro and in vivo.. Small cell lung cancer (SCLC) is characterized by a high relapse rate, drug tolerance, and limited treatment choices. Chimeric antigen receptor (CAR)-modified NK cells represent a promising immunotherapeutic modality for cancer treatment. However, their potential applications have not been explored …
Clinical
Program phase
PHASE_2