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항목
AntibodyStandard DatabasestalePhase 2
Bispecific antibody-based combined with CAR-T cell therapy (Bispecific antibody-based combined with CAR-T cell therapy)
Genentech, Inc.·B-cell Non-Hodgkin Lymphoma
3 trials
Overview
Program
Bispecific antibody-based combined with CAR-T cell therapy
Overview
Company
Genentech, Inc.
Overview
Modality
ANTIBODY
Overview
Target
B-cell Non-Hodgkin Lymphoma
Overview
Indication
B-cell Non-Hodgkin Lymphoma
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
Direct control of CAR T cells through small molecule-regulated antibodies.. Antibody-based therapeutics have experienced a rapid growth in recent years and are now utilized in various modalities spanning from conventional antibodies, antibody-drug conjugates, bispecific antibodies to chimeric antigen receptor (CAR) T cells. Many next generation antibody therapeutics achieve enhanced potency but of…
Toxicology
CRS
Reported
Clinical
Safety signal
Direct control of CAR T cells through small molecule-regulated antibodies.. Antibody-based therapeutics have experienced a rapid growth in recent years and are now utilized in various modalities spanning from conventional antibodies, antibody-drug conjugates, bispecific antibodies to chimeric antigen receptor (CAR) T cells. Many next generation antibody therapeutics achieve enhanced potency but of…
Clinical
Program phase
PHASE_2