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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-4 · 마지막 9월 2일

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프로그램 선택

API CSV15행 · 1개 프로그램
OverviewToxicologyClinical

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항목
CGTStandard DatabasestalePhase 1
anti-CEA CAR-T cells (anti-CEA CAR-T cells)
Roger Williams Medical Center·CEA
1 trials
Overview
Program
anti-CEA CAR-T cells
Overview
Company
Roger Williams Medical Center
Overview
Modality
CGT
Overview
Target
CEA
Overview
Indication
Liver Metastases
Overview
Phase
PHASE_1
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
Toxicology
Major finding
PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer.. The immunosuppressive microenvironment negatively affects the efficacy of chimeric antigen receptor T (CAR-T) cells in solid tumors. Fusion protein that combining extracellular domain of inhibitory checkpoint protein and the cytoplasmic domain of stimulatory molecule may improve the efficacy of CAR-T cells by…
Toxicology
CRS
Reported
Clinical
Safety signal
PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer.. The immunosuppressive microenvironment negatively affects the efficacy of chimeric antigen receptor T (CAR-T) cells in solid tumors. Fusion protein that combining extracellular domain of inhibitory checkpoint protein and the cytoplasmic domain of stimulatory molecule may improve the efficacy of CAR-T cells by…
Clinical
Program phase
PHASE_1