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항목
CGTStandard DatabasestalePhase 1
Anti-CD33 CAR T-cells (Anti-CD33 CAR T-cells)
iCell Gene Therapeutics·CD33
12 trials
Overview
Program
Anti-CD33 CAR T-cells
Overview
Company
iCell Gene Therapeutics
Overview
Modality
CGT
Overview
Target
CD33
Overview
Indication
Relapsed and/or Refractory Acute Myeloid Leukemia; High Risk Hematologic Malignancies
Overview
Phase
PHASE_1
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
Toxicology
Major finding
A phase 1/2 study of donor-derived anti-CD33 CAR T-cell therapy (VCAR33) for relapsed/refractory AML after allogeneic HCT.. VCAR33, a donor-derived CD33-directed chimeric antigen receptor T-cell (CAR T) product, was developed to decrease relapse of high-risk acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) after allogeneic hematopoietic cell transplantation (alloHCT). We describe pre…
Toxicology
CRS
Reported
Clinical
Safety signal
A phase 1/2 study of donor-derived anti-CD33 CAR T-cell therapy (VCAR33) for relapsed/refractory AML after allogeneic HCT.. VCAR33, a donor-derived CD33-directed chimeric antigen receptor T-cell (CAR T) product, was developed to decrease relapse of high-risk acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) after allogeneic hematopoietic cell transplantation (alloHCT). We describe pre…
Clinical
Program phase
PHASE_1