구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | ALTCAR.CD30 cells |
Overview Company | UNC Lineberger Comprehensive Cancer Center |
Overview Modality | CGT |
Overview Target | CD30 |
Overview Indication | Lymphoma; Immune System Diseases |
Overview Phase | PHASE_1 |
Overview Status | RECRUITING |
Overview Content status | Standard Database |
Overview Data Confidence | Data Confidence · Medium |
Overview Development Signal | Development Signal · Watch |
Overview Approval status | Investigational |
Toxicology Major finding | De novo design of miniproteins targeting GPCRs.. G protein-coupled receptors (GPCRs) play key roles in physiology and are central targets for drug discovery and development 1,2 , but the design of protein agonists and antagonists has been challenging as GPCRs are integral membrane proteins and conformationally dynamic 3-6 . Here we describe computational de novo design methods and a high-throughpu… |
Toxicology CRS | Reported |
Clinical Safety signal | De novo design of miniproteins targeting GPCRs.. G protein-coupled receptors (GPCRs) play key roles in physiology and are central targets for drug discovery and development 1,2 , but the design of protein agonists and antagonists has been challenging as GPCRs are integral membrane proteins and conformationally dynamic 3-6 . Here we describe computational de novo design methods and a high-throughpu… |
Clinical Program phase | PHASE_1 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | ALTCAR.CD30 cells |
Overview Company | UNC Lineberger Comprehensive Cancer Center |
Overview Modality | CGT |
Overview Target | CD30 |
Overview Indication | Lymphoma; Immune System Diseases |
Overview Phase | PHASE_1 |
Overview Status | RECRUITING |
Overview Content status | Standard Database |
Overview Data Confidence | Data Confidence · Medium |
Overview Development Signal | Development Signal · Watch |
Overview Approval status | Investigational |
Toxicology Major finding | De novo design of miniproteins targeting GPCRs.. G protein-coupled receptors (GPCRs) play key roles in physiology and are central targets for drug discovery and development 1,2 , but the design of protein agonists and antagonists has been challenging as GPCRs are integral membrane proteins and conformationally dynamic 3-6 . Here we describe computational de novo design methods and a high-throughpu… |
Toxicology CRS | Reported |
Clinical Safety signal | De novo design of miniproteins targeting GPCRs.. G protein-coupled receptors (GPCRs) play key roles in physiology and are central targets for drug discovery and development 1,2 , but the design of protein agonists and antagonists has been challenging as GPCRs are integral membrane proteins and conformationally dynamic 3-6 . Here we describe computational de novo design methods and a high-throughpu… |
Clinical Program phase | PHASE_1 |
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