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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-8 · 마지막 7월 21일

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프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.

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항목
AntibodyPhase 2
Bendamustine + Rituximab (Bendamustine + Rituximab)
Roche / Genentech·Chronic Lymphocytic Leukemia
ORR 95%
Overview
Program
Bendamustine + Rituximab
Overview
Company
Roche / Genentech
Overview
Modality
ANTIBODY
Overview
Target
Chronic Lymphocytic Leukemia
Overview
Indication
Marginal Zone Lymphoma(MZL)
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
MoA
Mechanism
targets the B-cell antigen
MoA
Biomarker
biomarker data at diagnosis were included in the survival analysis
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
pharmacokinetic
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
Bendamustine/Rituximab Induction Followed by Venetoclax/Rituximab Consolidation in Frontline Treatment of Chronic Lymphocytic Leukemia: A Phase 2 Multi-Center Study.. We hypothesized that a time-limited frontline treatment strategy with abbreviated chemoimmunotherapy followed by targeted consolidation could achieve durable disease control with manageable toxicity in CLL. We evaluated the safety an…
Toxicology
CRS
Reported
Clinical
Primary efficacy
ORR 95%
Clinical
ORR
95.0%
Clinical
Result source
ClinicalTrials.gov NCT02596971
Clinical
Data Tier / Score
A · 62
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 7월 18일 (8일 전)