구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | durvalumab (Imfinzi, Adjuvant durvalumab) ETOP IBCSG Partners Foundation·Non Small Cell Lung Cancer 31 trials |
|---|---|
Overview Program | Adjuvant durvalumab |
Overview Company | ETOP IBCSG Partners Foundation |
Overview Modality | ANTIBODY |
Overview Target | Non Small Cell Lung Cancer |
Overview Indication | Non Small Cell Lung Cancer |
Overview Phase | PHASE_3 |
Overview Status | RECRUITING |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | targeted therapies, particularly fibroblast growth factor receptor |
MoA Biomarker | PD-1/PD-L1 based regimens and > 10-fold high |
PK/PD Species | Clinical |
PK/PD Animal (cat.) | Unknown |
PK/PD Experiment | PD |
Toxicology Species | Clinical |
Toxicology Animal (cat.) | Unknown |
Toxicology Major finding | pneumonitis after adjuvant durvalumab in NSCLC patients treated with concurrent chemoradiot |
Toxicology CRS | 46% |
Clinical Safety signal | pneumonitis after adjuvant durvalumab in NSCLC patients treated with concurrent chemoradiot |
Clinical Selected reported efficacy | ORR 45% |
Clinical Reported ORR | 45% |
Clinical Reported PFS | 37 |
Clinical Result source | ClinicalTrials.gov NCT03141359 |
Clinical Program phase | PHASE_3 |
Clinical Trial ref | NCT03141359 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-5 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | durvalumab (Imfinzi, Adjuvant durvalumab) ETOP IBCSG Partners Foundation·Non Small Cell Lung Cancer 31 trials |
|---|---|
Overview Program | Adjuvant durvalumab |
Overview Company | ETOP IBCSG Partners Foundation |
Overview Modality | ANTIBODY |
Overview Target | Non Small Cell Lung Cancer |
Overview Indication | Non Small Cell Lung Cancer |
Overview Phase | PHASE_3 |
Overview Status | RECRUITING |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | targeted therapies, particularly fibroblast growth factor receptor |
MoA Biomarker | PD-1/PD-L1 based regimens and > 10-fold high |
PK/PD Species | Clinical |
PK/PD Animal (cat.) | Unknown |
PK/PD Experiment | PD |
Toxicology Species | Clinical |
Toxicology Animal (cat.) | Unknown |
Toxicology Major finding | pneumonitis after adjuvant durvalumab in NSCLC patients treated with concurrent chemoradiot |
Toxicology CRS | 46% |
Clinical Safety signal | pneumonitis after adjuvant durvalumab in NSCLC patients treated with concurrent chemoradiot |
Clinical Selected reported efficacy | ORR 45% |
Clinical Reported ORR | 45% |
Clinical Reported PFS | 37 |
Clinical Result source | ClinicalTrials.gov NCT03141359 |
Clinical Program phase | PHASE_3 |
Clinical Trial ref | NCT03141359 |
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