Compare molecular families | 바이오정보모아 구조

How similarity is calculated

보내기

KRAS G12C inhibitor chemical landscape

KRAS inhibitor

화합물 5
관계 7
SMILES 5/5

Drug: 5

KRAS G12C inhibitor chemical landscape. Independently sourced molecular structures from PubChem. Family membership is an editorial grouping, not evidence of a shared scaffold, synthesis route, or clinical performance.

Daraxonrasib · RAS(ON)

KRAS inhibitor

화합물 3
관계 1
SMILES 3/3

Drug: 1
Linker: 2

Non-covalent RAS(ON) multi-selective inhibitor. Independently sourced molecular structures from PubChem. Family membership is an editorial grouping, not evidence of a shared scaffold, synthesis route, or clinical performance.

KRAS G12D / RAS(ON) inhibitor series

KRAS inhibitor

화합물 3
관계 1
SMILES 3/3

Drug: 3

KRAS G12D / RAS(ON) inhibitor series. Independently sourced molecular structures from PubChem. Family membership is an editorial grouping, not evidence of a shared scaffold, synthesis route, or clinical performance.

패밀리 간 overlap

kras-g12c ↔ daraxonrasib · 평균 유사도(상위 쌍): 0.13
kras-g12c ↔ kras-g12d · 평균 유사도(상위 쌍): 0.15
daraxonrasib ↔ kras-g12d · 평균 유사도(상위 쌍): 0.24

Core-compound Morgan similarity

Morgan fingerprint, radius 2, 2048 bits, Tanimoto. This value does not predict potency, biological activity, safety, or clinical efficacy.

	KRAS G12C inhibitor chemical landscape	Daraxonrasib · RAS(ON)	KRAS G12D / RAS(ON) inhibitor series
KRAS G12C inhibitor chemical landscape	1.00	0.13	0.14
Daraxonrasib · RAS(ON)	0.13	1.00	0.15
KRAS G12D / RAS(ON) inhibitor series	0.14	0.15	1.00

How similarity is calculated

보내기

KRAS G12C inhibitor chemical landscape

KRAS inhibitor

화합물 5
관계 7
SMILES 5/5

Drug: 5

KRAS G12C inhibitor chemical landscape. Independently sourced molecular structures from PubChem. Family membership is an editorial grouping, not evidence of a shared scaffold, synthesis route, or clinical performance.

Daraxonrasib · RAS(ON)

KRAS inhibitor

화합물 3
관계 1
SMILES 3/3

Drug: 1
Linker: 2

Non-covalent RAS(ON) multi-selective inhibitor. Independently sourced molecular structures from PubChem. Family membership is an editorial grouping, not evidence of a shared scaffold, synthesis route, or clinical performance.

KRAS G12D / RAS(ON) inhibitor series

KRAS inhibitor

화합물 3
관계 1
SMILES 3/3

Drug: 3

KRAS G12D / RAS(ON) inhibitor series. Independently sourced molecular structures from PubChem. Family membership is an editorial grouping, not evidence of a shared scaffold, synthesis route, or clinical performance.

패밀리 간 overlap

kras-g12c ↔ daraxonrasib · 평균 유사도(상위 쌍): 0.13
kras-g12c ↔ kras-g12d · 평균 유사도(상위 쌍): 0.15
daraxonrasib ↔ kras-g12d · 평균 유사도(상위 쌍): 0.24

Core-compound Morgan similarity

Morgan fingerprint, radius 2, 2048 bits, Tanimoto. This value does not predict potency, biological activity, safety, or clinical efficacy.

	KRAS G12C inhibitor chemical landscape	Daraxonrasib · RAS(ON)	KRAS G12D / RAS(ON) inhibitor series
KRAS G12C inhibitor chemical landscape	1.00	0.13	0.14
Daraxonrasib · RAS(ON)	0.13	1.00	0.15
KRAS G12D / RAS(ON) inhibitor series	0.14	0.15	1.00