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항목
AntibodyCurated CorestaleApproved
Tralokinumab (Tralokinumab)
LEO Pharma·Atopic Dermatitis
43 trials
Overview
Program
Tralokinumab
Overview
Company
LEO Pharma
Overview
Modality
ANTIBODY
Overview
Target
Atopic Dermatitis
Overview
Indication
Psoriasis; Atopic Dermatitis
Overview
Phase
APPROVED
Overview
Status
RECRUITING
Overview
Content status
Curated Core
Overview
Data Confidence
Data Confidence · High
Overview
Development Signal
Development Signal · Established
Overview
Approval status
Approved (flag incomplete)
Positioning
Key differentiator
Novel systemic treatments can not only provide effective relief for these patients but can also be cost saving
MoA
Mechanism
is still under investigation (5,6)
MoA
Biomarker
biomarker transition, and safety of 48-week tralokinumab treatment for atopic dermatitis: real-world analyses
PK/PD
Animal (cat.)
Human
PK/PD
Experiment
pd
Toxicology
Animal (cat.)
Human
Toxicology
Major finding
Effectiveness, biomarker transition, and safety of 48-week tralokinumab treatment for atopic dermatitis: real-world analyses stratified by age groups (15-17, 18-64, and ≥ 65 years).. Tralokinumab, an anti-interleukin-13 monoclonal antibody, is effective for atopic dermatitis (AD). However, long-term (one-year) clinical outcomes stratified by age groups have not been sufficiently studied. To…
Clinical
Safety signal
Effectiveness, biomarker transition, and safety of 48-week tralokinumab treatment for atopic dermatitis: real-world analyses stratified by age groups (15-17, 18-64, and ≥ 65 years).. Tralokinumab, an anti-interleukin-13 monoclonal antibody, is effective for atopic dermatitis (AD). However, long-term (one-year) clinical outcomes stratified by age groups have not been sufficiently studied. To…
Clinical
Selected reported efficacy
100%
Clinical
Result source
ClinicalTrials.gov NCT02684097
Clinical
Program phase
APPROVED
Clinical
Trial ref
NCT02684097