구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | protein analysis (protein analysis) The Scientific and Technological R…·Chronic Myeloproliferative Disorde… 93 trials |
|---|---|
Overview Program | protein analysis |
Overview Company | The Scientific and Technological Research Council of Turkey |
Overview Modality | ANTIBODY |
Overview Target | Chronic Myeloproliferative Disorders |
Overview Indication | Chronic Myeloproliferative Disorders; Leukemia |
Overview Phase | PHASE_2 |
Overview Status | DISCONTINUED |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | target within the Kras signalling pathway |
MoA Biomarker | Biomarkers in Patients With Rheumatoid Arthritis but Normal ESR/CRP Receiving Biological/Targeted Synthetic D |
PK/PD Species | Mouse, Rat |
PK/PD Animal (cat.) | Human, Mouse, Rat, In vitro |
PK/PD Experiment | PD |
Toxicology Species | Mouse, Rat |
Toxicology Animal (cat.) | Human, Mouse, Rat, In vitro |
Toxicology Major finding | Exposure of dairy goat mammary epithelial cells to bis(2-ethylhexyl) phthalate induces oxidative stress and alters gene/protein expression, posing health risks.. The goat milk industry is expanding, yet the toxic effects of bis(2-ethylhexyl) phthalate (DEHP) on goat mammary glands remain understudied despite extensive in vivo research in mice and humans. This study used mammary epithelial cells to… |
Clinical Safety signal | Exposure of dairy goat mammary epithelial cells to bis(2-ethylhexyl) phthalate induces oxidative stress and alters gene/protein expression, posing health risks.. The goat milk industry is expanding, yet the toxic effects of bis(2-ethylhexyl) phthalate (DEHP) on goat mammary glands remain understudied despite extensive in vivo research in mice and humans. This study used mammary epithelial cells to… |
Clinical Reported PFS | 0.263 |
Clinical Reported OS | 5.58 |
Clinical Result source | ClinicalTrials.gov NCT00621686 |
Clinical Program phase | PHASE_2 |
Clinical Trial activity | No active/completed counts |
Clinical Trial ref | NCT00621686 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | protein analysis (protein analysis) The Scientific and Technological R…·Chronic Myeloproliferative Disorde… 93 trials |
|---|---|
Overview Program | protein analysis |
Overview Company | The Scientific and Technological Research Council of Turkey |
Overview Modality | ANTIBODY |
Overview Target | Chronic Myeloproliferative Disorders |
Overview Indication | Chronic Myeloproliferative Disorders; Leukemia |
Overview Phase | PHASE_2 |
Overview Status | DISCONTINUED |
Overview Content status | Limited Data |
Overview Data Confidence | Data Confidence · Low |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
MoA Mechanism | target within the Kras signalling pathway |
MoA Biomarker | Biomarkers in Patients With Rheumatoid Arthritis but Normal ESR/CRP Receiving Biological/Targeted Synthetic D |
PK/PD Species | Mouse, Rat |
PK/PD Animal (cat.) | Human, Mouse, Rat, In vitro |
PK/PD Experiment | PD |
Toxicology Species | Mouse, Rat |
Toxicology Animal (cat.) | Human, Mouse, Rat, In vitro |
Toxicology Major finding | Exposure of dairy goat mammary epithelial cells to bis(2-ethylhexyl) phthalate induces oxidative stress and alters gene/protein expression, posing health risks.. The goat milk industry is expanding, yet the toxic effects of bis(2-ethylhexyl) phthalate (DEHP) on goat mammary glands remain understudied despite extensive in vivo research in mice and humans. This study used mammary epithelial cells to… |
Clinical Safety signal | Exposure of dairy goat mammary epithelial cells to bis(2-ethylhexyl) phthalate induces oxidative stress and alters gene/protein expression, posing health risks.. The goat milk industry is expanding, yet the toxic effects of bis(2-ethylhexyl) phthalate (DEHP) on goat mammary glands remain understudied despite extensive in vivo research in mice and humans. This study used mammary epithelial cells to… |
Clinical Reported PFS | 0.263 |
Clinical Reported OS | 5.58 |
Clinical Result source | ClinicalTrials.gov NCT00621686 |
Clinical Program phase | PHASE_2 |
Clinical Trial activity | No active/completed counts |
Clinical Trial ref | NCT00621686 |
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