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항목
CGTStandard DatabasestalePreclinical
morphine sulfate (morphine sulfate)
Mundipharma (China) Pharmaceutical…·Brain and Central Nervous System T…
61 trials·t½ 15 h
Overview
Program
morphine sulfate
Overview
Company
Mundipharma (China) Pharmaceutical Co. Ltd
Overview
Modality
CGT
Overview
Target
Brain and Central Nervous System Tumors
Overview
Indication
Brain and Central Nervous System Tumors; Chronic Myeloproliferative Disorders
Overview
Phase
PRECLINICAL
Overview
Status
DISCONTINUED
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
MoA
Mechanism
targeting both μ- and δ-opioid receptor
MoA
Biomarker
biomarker of substance abuse-were analysed
PK/PD
Half-life
15 h
PK/PD
Species
Rat
PK/PD
Animal (cat.)
Rat
PK/PD
Experiment
pharmacokinetic
Toxicology
Species
Rat
Toxicology
Animal (cat.)
Rat
Toxicology
Major finding
Ketamine versus morphine for musculoskeletal trauma pain: a meta-analysis of randomized controlled trials.. Pain is a primary reason for emergency department visits and hospitalizations following injuries, and its inadequate management can lead to complications. Effective and safe pain control is crucial in traumatic patient management. Opioids like morphine are commonly used for acute pain due to…
Clinical
Safety signal
Ketamine versus morphine for musculoskeletal trauma pain: a meta-analysis of randomized controlled trials.. Pain is a primary reason for emergency department visits and hospitalizations following injuries, and its inadequate management can lead to complications. Effective and safe pain control is crucial in traumatic patient management. Opioids like morphine are commonly used for acute pain due to…
Clinical
Program phase
PRECLINICAL