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API CSV26행 · 1개 프로그램

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항목
CGTStandard DatabasestalePreclinical
Lung cancer cohort (Lung cancer cohort)
Centre Leon Berard·Breast Cancer
60 trials
Overview
Program
Lung cancer cohort
Overview
Company
Centre Leon Berard
Overview
Modality
CGT
Overview
Target
Breast Cancer
Overview
Indication
Breast Cancer; Lung Cancer
Overview
Phase
PRECLINICAL
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
MoA
Mechanism
Targetable S100-RAGE signaling
MoA
Biomarker
biomarker testing, financial coverage, toxicity, treatment discontinuation, clinical benefit, progression-fre
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
interstitial lung disease (CT‑ILD) is a serious and potentially fatal complication in lung
Clinical
Safety signal
interstitial lung disease (CT‑ILD) is a serious and potentially fatal complication in lung
Clinical
Selected reported efficacy
ORR 56.3%
Clinical
Reported ORR
56.3%
Clinical
Reported PFS
8.4
Clinical
Result source
ClinicalTrials.gov NCT03308942
Clinical
Program phase
PRECLINICAL
Clinical
Trial ref
NCT03308942