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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일

현재 선택: 1 · 임상 갱신 필요 1

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API CSV19행 · 1개 프로그램

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항목
CGTStandard DatabasestalePhase 3
Liso-cel (Liso-cel)
Juno Therapeutics, Inc., a Bristol…·FRα
30 trials
Overview
Program
Liso-cel
Overview
Company
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Overview
Modality
CGT
Overview
Target
FRα
Overview
Indication
Relapsed or Refractory Follicular Lymphoma
Overview
Phase
PHASE_3
Overview
Status
DISCONTINUED
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
A new era for transplant-ineligible R/R LBCL patients: what's changing?. Most patients with large B-cell lymphoma (LBCL) are cured with frontline chemoimmunotherapy; however, 30-40% experience relapsed or refractory (R/R) disease. Historically, salvage chemotherapy followed by autologous stem cell transplantation (ASCT) represented the standard second-line treatment. Several studies have demonstra…
Toxicology
CRS
Reported
Clinical
Safety signal
A new era for transplant-ineligible R/R LBCL patients: what's changing?. Most patients with large B-cell lymphoma (LBCL) are cured with frontline chemoimmunotherapy; however, 30-40% experience relapsed or refractory (R/R) disease. Historically, salvage chemotherapy followed by autologous stem cell transplantation (ASCT) represented the standard second-line treatment. Several studies have demonstra…
Clinical
Selected reported efficacy
ORR 53.7%
Clinical
Reported ORR
53.7%
Clinical
Result source
ClinicalTrials.gov NCT03744676
Clinical
Program phase
PHASE_3
Clinical
Trial ref
NCT03744676