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항목
CGTStandard DatabasestalePhase 3
Lapine T-Lymphocyte Immune Globulin (Lapine T-Lymphocyte Immune Globulin)
M.D. Anderson Cancer Center·Acute Lymphoblastic Leukemia
32 trials
Overview
Program
Lapine T-Lymphocyte Immune Globulin
Overview
Company
M.D. Anderson Cancer Center
Overview
Modality
CGT
Overview
Target
Acute Lymphoblastic Leukemia
Overview
Indication
Beta Thalassemia Major; Sickle Beta 0 Thalassemia
Overview
Phase
PHASE_3
Overview
Status
RECRUITING
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
MoA
Biomarker
biomarkers of immunotherapy response in new-onset type 1 diabetes
PK/PD
Species
Rabbit, Human
PK/PD
Animal (cat.)
Human
PK/PD
Experiment
Pharmacokinetic
Toxicology
Species
Rabbit, Human
Toxicology
Animal (cat.)
Human
Toxicology
Major finding
thrombocytopenia, graft loss, and acute rejection
Toxicology
CRS
Reported
Clinical
Safety signal
thrombocytopenia, graft loss, and acute rejection
Clinical
Reported PFS
24
Clinical
Reported OS
25
Clinical
Result source
ClinicalTrials.gov NCT00572897
Clinical
Program phase
PHASE_3
Clinical
Trial ref
NCT00572897
Preclinical
Animal (cat.)
Human, NHP, In vitro