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항목
CGTStandard DatabasestalePhase 2
L-Asparaginase (L-Asparaginase)
Genentech, Inc.·B Lymphoblastic Leukemia
58 trials
Overview
Program
L-Asparaginase
Overview
Company
Genentech, Inc.
Overview
Modality
CGT
Overview
Target
B Lymphoblastic Leukemia
Overview
Indication
B Lymphoblastic Leukemia
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
MoA
Mechanism
target of rapamycin (mTOR), the other major amino acid-sensing pathway
MoA
Biomarker
biomarkers
PK/PD
Species
Mouse, Human
PK/PD
Animal (cat.)
Human, Mouse, In vitro
PK/PD
Experiment
PK
Toxicology
Species
Mouse, Human
Toxicology
Animal (cat.)
Human, Mouse, In vitro
Toxicology
Major finding
Pleurotus ostreatus L-asparaginase's use in food safety and biotechnology: from processing assistance to bioactive agent.. L-ASNase has attracted attention in many biomedical and food safety applications. Therefore, this study was designed to identify a novel and promising candidate for the sustainable biosynthesis of extracellular L-ASNase from P. ostreatus AUMC 16015 grown on various agricu…
Clinical
Safety signal
Pleurotus ostreatus L-asparaginase's use in food safety and biotechnology: from processing assistance to bioactive agent.. L-ASNase has attracted attention in many biomedical and food safety applications. Therefore, this study was designed to identify a novel and promising candidate for the sustainable biosynthesis of extracellular L-ASNase from P. ostreatus AUMC 16015 grown on various agricu…
Clinical
Reported OS
33.6
Clinical
Result source
ClinicalTrials.gov NCT00061945
Clinical
Program phase
PHASE_2
Clinical
Trial ref
NCT00061945