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API CSV19행 · 1개 프로그램

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항목
CGTStandard DatabasestalePhase 2
KTE-X19 (KTE-X19)
Kite, A Gilead Company·Mantle Cell Lymphoma
12 trials
Overview
Program
KTE-X19
Overview
Company
Kite, A Gilead Company
Overview
Modality
CGT
Overview
Target
Mantle Cell Lymphoma
Overview
Indication
Mantle Cell Lymphoma
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
Toxicology
Major finding
CAR T-Cell therapy for the management of mantle cell lymphoma.. Mantle cell lymphoma (MCL) is a subtype of Non-Hodgkin lymphoma (NHL) of mature B-cells characterized by translocation, which is typically due to excess expression of Cyclin D1. Although with the progress in our knowledge of the causes for MCL and available treatments for MCL, this cancer is still incurable. Age, male gender, rapid ad…
Toxicology
CRS
Reported
Clinical
Safety signal
CAR T-Cell therapy for the management of mantle cell lymphoma.. Mantle cell lymphoma (MCL) is a subtype of Non-Hodgkin lymphoma (NHL) of mature B-cells characterized by translocation, which is typically due to excess expression of Cyclin D1. Although with the progress in our knowledge of the causes for MCL and available treatments for MCL, this cancer is still incurable. Age, male gender, rapid ad…
Clinical
Selected reported efficacy
ORR 86%
Clinical
Reported ORR
86%
Clinical
Result source
ClinicalTrials.gov NCT02601313
Clinical
Program phase
PHASE_2
Clinical
Trial ref
NCT02601313