구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Golimumab (Golimumab) Belfast Health and Social Care Tru…·Chronic Nonbacterial Osteomyelitis 80 trials·t½ 3 h |
|---|---|
Overview Program | Golimumab |
Overview Company | Belfast Health and Social Care Trust |
Overview Modality | ANTIBODY |
Overview Target | Chronic Nonbacterial Osteomyelitis |
Overview Indication | Psoriatic Arthritis; Psoriasis |
Overview Phase | APPROVED |
Overview Status | DISCONTINUED |
Overview Content status | Curated Core |
Overview Data Confidence | Data Confidence · High |
Overview Development Signal | Development Signal · Established |
Overview Approval status | Approved (flag incomplete) |
Positioning Key differentiator | Novel Activated NK-Associated Gene Score Associated with Diagnosis and Biological Therapy Response in Ulcerative Colitis |
MoA Mechanism | s and infections appeared limited |
MoA Biomarker | biomarker, endoscopic, and histological outcomes were evaluated at weeks 16 and 52 |
PK/PD Half-life | 3 h |
PK/PD Species | Cynomolgus monkey, NHP, Marmoset |
PK/PD Animal (cat.) | Human, NHP |
PK/PD Experiment | Pharmacokinetic |
Toxicology Species | Cynomolgus monkey, NHP, Marmoset |
Toxicology Animal (cat.) | Human, NHP |
Toxicology Major finding | Real-world effectiveness and safety of golimumab in ulcerative colitis: multicenter experience from Chile.. Evidence on golimumab for ulcerative colitis (UC) is scarce in Latin America. We aimed to assess the real-world effectiveness and safety of golimumab in a multicenter Chilean cohort. We conducted a retrospective, observational study including adult patients with moderate-to-severe UC treated… |
Clinical Safety signal | Real-world effectiveness and safety of golimumab in ulcerative colitis: multicenter experience from Chile.. Evidence on golimumab for ulcerative colitis (UC) is scarce in Latin America. We aimed to assess the real-world effectiveness and safety of golimumab in a multicenter Chilean cohort. We conducted a retrospective, observational study including adult patients with moderate-to-severe UC treated… |
Clinical Result source | ClinicalTrials.gov NCT04200833 |
Clinical Program phase | APPROVED |
Clinical Trial ref | NCT04200833 |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Golimumab (Golimumab) Belfast Health and Social Care Tru…·Chronic Nonbacterial Osteomyelitis 80 trials·t½ 3 h |
|---|---|
Overview Program | Golimumab |
Overview Company | Belfast Health and Social Care Trust |
Overview Modality | ANTIBODY |
Overview Target | Chronic Nonbacterial Osteomyelitis |
Overview Indication | Psoriatic Arthritis; Psoriasis |
Overview Phase | APPROVED |
Overview Status | DISCONTINUED |
Overview Content status | Curated Core |
Overview Data Confidence | Data Confidence · High |
Overview Development Signal | Development Signal · Established |
Overview Approval status | Approved (flag incomplete) |
Positioning Key differentiator | Novel Activated NK-Associated Gene Score Associated with Diagnosis and Biological Therapy Response in Ulcerative Colitis |
MoA Mechanism | s and infections appeared limited |
MoA Biomarker | biomarker, endoscopic, and histological outcomes were evaluated at weeks 16 and 52 |
PK/PD Half-life | 3 h |
PK/PD Species | Cynomolgus monkey, NHP, Marmoset |
PK/PD Animal (cat.) | Human, NHP |
PK/PD Experiment | Pharmacokinetic |
Toxicology Species | Cynomolgus monkey, NHP, Marmoset |
Toxicology Animal (cat.) | Human, NHP |
Toxicology Major finding | Real-world effectiveness and safety of golimumab in ulcerative colitis: multicenter experience from Chile.. Evidence on golimumab for ulcerative colitis (UC) is scarce in Latin America. We aimed to assess the real-world effectiveness and safety of golimumab in a multicenter Chilean cohort. We conducted a retrospective, observational study including adult patients with moderate-to-severe UC treated… |
Clinical Safety signal | Real-world effectiveness and safety of golimumab in ulcerative colitis: multicenter experience from Chile.. Evidence on golimumab for ulcerative colitis (UC) is scarce in Latin America. We aimed to assess the real-world effectiveness and safety of golimumab in a multicenter Chilean cohort. We conducted a retrospective, observational study including adult patients with moderate-to-severe UC treated… |
Clinical Result source | ClinicalTrials.gov NCT04200833 |
Clinical Program phase | APPROVED |
Clinical Trial ref | NCT04200833 |
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