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현재 선택: 1 · 임상 갱신 필요 1

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API CSV26행 · 1개 프로그램

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항목
CGTStandard DatabasestalePhase 3
ciprofloxacin (ciprofloxacin)
Laboratorios Sophia S.A de C.V.·Brain and Central Nervous System T…
60 trials·t½ 2.52 h
Overview
Program
ciprofloxacin
Overview
Company
Laboratorios Sophia S.A de C.V.
Overview
Modality
CGT
Overview
Target
Brain and Central Nervous System Tumors
Overview
Indication
Brain and Central Nervous System Tumors; Lymphoma
Overview
Phase
PHASE_3
Overview
Status
ACTIVE
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Emerging
Overview
Approval status
Investigational
PK/PD
Half-life
2.52 h
PK/PD
Species
Rabbit
PK/PD
Animal (cat.)
Unknown
PK/PD
Experiment
pharmacokinetic
Toxicology
Species
Rabbit
Toxicology
Animal (cat.)
Unknown
Toxicology
Major finding
Restoring ciprofloxacin efficacy via β-caryophyllene synergy for concurrent infection control and tissue regeneration.. The occurrence of antimicrobial-resistant microbial infection on the wounds are considered a critical issue in delayed or non-healing wounds. Due to the scarcity of new antibiotics in the market, alternate combinational therapies are gaining interest in tackling this issue.…
Clinical
Safety signal
Restoring ciprofloxacin efficacy via β-caryophyllene synergy for concurrent infection control and tissue regeneration.. The occurrence of antimicrobial-resistant microbial infection on the wounds are considered a critical issue in delayed or non-healing wounds. Due to the scarcity of new antibiotics in the market, alternate combinational therapies are gaining interest in tackling this issue.…
Clinical
Selected reported efficacy
ORR 6%
Clinical
Reported ORR
15%
Clinical
Reported PFS
4.7
Clinical
Reported OS
11.2
Clinical
Result source
ClinicalTrials.gov NCT00332163
Clinical
Program phase
PHASE_3
Clinical
Trial ref
NCT00332163