구조모아 (StructureMoa)항암 chemical structure spider web
방문타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Autologous hematopoietic stem cell infusion (Autologous hematopoietic stem cell infusion) Institute of Hematology & Blood Di…·Prolonged Cytopenia Following CAR-… 31 trials |
|---|---|
Overview Program | Autologous hematopoietic stem cell infusion |
Overview Company | Institute of Hematology & Blood Diseases Hospital, China |
Overview Modality | CGT |
Overview Target | Prolonged Cytopenia Following CAR-T Ther |
Overview Indication | Prolonged Cytopenia Following CAR-T Therapy |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
Overview Content status | Standard Database |
Overview Data Confidence | Data Confidence · Medium |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
Technology Vector | lentiviral vector and used to transduce hematopoietic stem and progenitor cells (HSPCs) fr |
MoA Mechanism | , manufacturing processes and ongoing clinical trials |
MoA Biomarker | biomarker for treatment response and relapse prediction |
PK/PD Species | Mouse, Human |
PK/PD Animal (cat.) | Human, Mouse, In vitro |
PK/PD Experiment | Pharmacokinetic |
Toxicology Species | Mouse, Human |
Toxicology Animal (cat.) | Human, Mouse, In vitro |
Toxicology Major finding | thrombocytopenia was more common with HD-Ara-C, it was manageable with supportive care |
Toxicology CRS | Reported |
Clinical Safety signal | thrombocytopenia was more common with HD-Ara-C, it was manageable with supportive care |
Clinical Selected reported efficacy | 73.33% |
Clinical Result source | ClinicalTrials.gov NCT02722941 |
Clinical Program phase | PHASE_2 |
Clinical Trial ref | NCT02722941 |
Preclinical Animal (cat.) | Mouse, In vitro |
타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Autologous hematopoietic stem cell infusion (Autologous hematopoietic stem cell infusion) Institute of Hematology & Blood Di…·Prolonged Cytopenia Following CAR-… 31 trials |
|---|---|
Overview Program | Autologous hematopoietic stem cell infusion |
Overview Company | Institute of Hematology & Blood Diseases Hospital, China |
Overview Modality | CGT |
Overview Target | Prolonged Cytopenia Following CAR-T Ther |
Overview Indication | Prolonged Cytopenia Following CAR-T Therapy |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
Overview Content status | Standard Database |
Overview Data Confidence | Data Confidence · Medium |
Overview Development Signal | Development Signal · Emerging |
Overview Approval status | Investigational |
Technology Vector | lentiviral vector and used to transduce hematopoietic stem and progenitor cells (HSPCs) fr |
MoA Mechanism | , manufacturing processes and ongoing clinical trials |
MoA Biomarker | biomarker for treatment response and relapse prediction |
PK/PD Species | Mouse, Human |
PK/PD Animal (cat.) | Human, Mouse, In vitro |
PK/PD Experiment | Pharmacokinetic |
Toxicology Species | Mouse, Human |
Toxicology Animal (cat.) | Human, Mouse, In vitro |
Toxicology Major finding | thrombocytopenia was more common with HD-Ara-C, it was manageable with supportive care |
Toxicology CRS | Reported |
Clinical Safety signal | thrombocytopenia was more common with HD-Ara-C, it was manageable with supportive care |
Clinical Selected reported efficacy | 73.33% |
Clinical Result source | ClinicalTrials.gov NCT02722941 |
Clinical Program phase | PHASE_2 |
Clinical Trial ref | NCT02722941 |
Preclinical Animal (cat.) | Mouse, In vitro |
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