검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-8 · 마지막 7월 21일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | AdV-tk |
Overview Company | Candel Therapeutics, Inc. |
Overview Modality | ANTIBODY |
Overview Target | Glioma, Malignant |
Overview Indication | Malignant Glioma; Recurrent Ependymoma |
Overview Phase | PHASE_1 |
Overview Status | ACTIVE |
MoA Biomarker | biomarkers were evaluated in tumor and blood before and after GMCI |
PK/PD Species | Mouse, Human |
PK/PD Animal (cat.) | Human, Mouse |
PK/PD Experiment | biodistribution |
Toxicology Species | Mouse, Human |
Toxicology Animal (cat.) | Human, Mouse |
Toxicology Major finding | Phase I Study of Intrapleural Gene-Mediated Cytotoxic Immunotherapy in Patients with Malignant Pleural Effusion.. Gene-mediated cytotoxic immunotherapy (GMCI) is an immune strategy implemented through local delivery of an adenovirus-based vector expressing the thymidine kinase gene (aglatimagene besadenovec, AdV-tk) followed by anti-herpetic prodrug valacyclovir. A phase I dose escalation trial of… |
Toxicology CRS | grade 2 |
Clinical ORR | 11% |
Clinical PFS | 0 |
Clinical OS | 15 |
Clinical Result source | ClinicalTrials.gov NCT02831933 |
Clinical Data Tier / Score | A · 34 |
Clinical Program phase | PHASE_1 |
Clinical Clinical sync | 2026년 7월 18일 (8일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-8 · 마지막 7월 21일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | AdV-tk |
Overview Company | Candel Therapeutics, Inc. |
Overview Modality | ANTIBODY |
Overview Target | Glioma, Malignant |
Overview Indication | Malignant Glioma; Recurrent Ependymoma |
Overview Phase | PHASE_1 |
Overview Status | ACTIVE |
MoA Biomarker | biomarkers were evaluated in tumor and blood before and after GMCI |
PK/PD Species | Mouse, Human |
PK/PD Animal (cat.) | Human, Mouse |
PK/PD Experiment | biodistribution |
Toxicology Species | Mouse, Human |
Toxicology Animal (cat.) | Human, Mouse |
Toxicology Major finding | Phase I Study of Intrapleural Gene-Mediated Cytotoxic Immunotherapy in Patients with Malignant Pleural Effusion.. Gene-mediated cytotoxic immunotherapy (GMCI) is an immune strategy implemented through local delivery of an adenovirus-based vector expressing the thymidine kinase gene (aglatimagene besadenovec, AdV-tk) followed by anti-herpetic prodrug valacyclovir. A phase I dose escalation trial of… |
Toxicology CRS | grade 2 |
Clinical ORR | 11% |
Clinical PFS | 0 |
Clinical OS | 15 |
Clinical Result source | ClinicalTrials.gov NCT02831933 |
Clinical Data Tier / Score | A · 34 |
Clinical Program phase | PHASE_1 |
Clinical Clinical sync | 2026년 7월 18일 (8일 전) |
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