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타깃 · 모달리티 · 임상 근거 · 비임상 맥락으로 최대 5개 프로그램을 나란히 비교합니다. · 다음 갱신 D-6 · 마지막 9월 2일

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항목
CGTStandard DatabasePhase 1
19 (T2, 19, 19(T2)28z1xx TRAC T cell)
GlaxoSmithKline·B-Cell Lymphoma
340 trials
Overview
Program
19(T2)28z1xx TRAC T cell
Overview
Company
GlaxoSmithKline
Overview
Modality
CGT
Overview
Target
B-Cell Lymphoma
Overview
Indication
B-Cell Lymphoma; Large B-cell Lymphoma
Overview
Phase
PHASE_1
Overview
Status
RECRUITING
Overview
Content status
Standard Database
Overview
Data Confidence
Data Confidence · Medium
Overview
Development Signal
Development Signal · Watch
Overview
Approval status
Investigational
MoA
Mechanism
ADC and SDC of 1 rat study with liver fibrosis induced by biliary duct ligation (BDL), and 3 sets of human liver fibrosis data
MoA
Biomarker
biomarkers, enhanced trial matching, and scalable cohort identification
PK/PD
Species
Mouse, Rat, Human
PK/PD
Animal (cat.)
Human, Mouse, Rat, In vitro
PK/PD
Experiment
PK
Toxicology
Species
Human
Toxicology
Animal (cat.)
Human
Toxicology
Major finding
Awake emergency laparotomy under combined spinal epidural anaesthesia in a high-risk patient with severe pulmonary disease and neuromuscular blocking agent anaphylaxis.. Bowel obstruction is a prevalent surgical emergency, particularly among the elderly, necessitating prompt intervention. Emergency laparotomy is associated with high morbidity and mortality, particularly in frail elderly patients w…
Clinical
Safety signal
Awake emergency laparotomy under combined spinal epidural anaesthesia in a high-risk patient with severe pulmonary disease and neuromuscular blocking agent anaphylaxis.. Bowel obstruction is a prevalent surgical emergency, particularly among the elderly, necessitating prompt intervention. Emergency laparotomy is associated with high morbidity and mortality, particularly in frail elderly patients w…
Clinical
Selected reported efficacy
ORR 100%
Clinical
Reported ORR
100%
Clinical
Result source
ClinicalTrials.gov NCT04750941
Clinical
Program phase
PHASE_1
Clinical
Trial activity
No active/completed counts
Clinical
Trial ref
NCT04750941